Investigación Aplicada: Recent submissions
Now showing items 121-140 of 225
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Results of Liver Transplantation for Hepatocellular Carcinoma in a Multicenter Latin American Cohort Study.
(Fundación Clínica Médica Sur, A.C., 2018-03-01)Background and aims. Heterogeneous data has been reported regarding liver transplantation (LT) for hepatocellular carcinoma (HCC) in Latin America. We aimed to describe treatment during waiting list, survival and recurrence ... -
Fatty liver disease, an emerging etiology of hepatocellular carcinoma in Argentina.
(Baishideng Publishing Group, 2018-01-27)AIM: To investigate any changing trends in the etiologies of hepatocellular carcinoma (HCC) in Argentina during the last years. METHODS: A longitudinal cohort study was conducted by 14 regional hospitals starting in ... -
Incidence, risk factors, and outcomes related with neurological events after liver transplantation in adult and pediatric recipients.
(Wiley, 2018-02-07)Controversy exists whether NE after LT are more frequently observed in children or adults. We aimed to compare the incidence and outcomes for NE after LT in pediatric and adult recipients. A single-center cohort study, ... -
Tolvaptan in Later-Stage Autosomal Dominant Polycystic Kidney Disease.
(Massachusetts Medical Society, 2017-11-16)BACKGROUND: In a previous trial involving patients with early autosomal dominant polycystic kidney disease (ADPKD; estimated creatinine clearance, ≥60 ml per minute), the vasopressin V2-receptor antagonist tolvaptan slowed ... -
Dropout rate from the liver transplant waiting list because of hepatocellular carcinoma progression in hepatitis C virus-infected patients treated with direct-acting antivirals.
(Wiley, 2017-10-01)We have read with interest the article recently pub-lished by Zanetto et al. inLiver Transplantationregarding the effect on radiologic progression of hepa-tocellular carcinoma (HCC) after the treatment withdirect-acting ... -
Prevalencia y características clínicas del asma en adultos jóvenes en zonas urbanas de Argentina
(Elsevier, 2018-03-01)Objetivo Estimar la carga del asma en la población adulta joven en zonas urbanas de Argentina. Diseño Se realizó una encuesta telefónica a nivel nacional en sujetos de 20 a 44 años en áreas urbanas de Argentina. Se ... -
Schwann cell precursors in health and disease.
(Wiley, 2017-11-10)Schwann cell precursors (SCPs) are frequently regarded as neural crest-derived cells (NCDCs) found in contact with axons during nerve formation. Nevertheless, cells with SCPs properties can be found up to the adulthood. ... -
Hematopoietic Stem-Cell Gene Therapy for Cerebral Adrenoleukodystrophy.
(Massachusetts Medical Society, 2017-10-26)BACKGROUND: In X-linked adrenoleukodystrophy, mutations in ABCD1 lead to loss of function of the ALD protein. Cerebral adrenoleukodystrophy is characterized by demyelination and neurodegeneration. Disease progression, ... -
Developing multicenter consortia in liver disease in Latin America: Challenges and opportunities.
(Wiley, 2017-06-07)The development of consortia has been useful for exploring challenging scenarios and uncharted territories in liver disease treatments. Several consortia already developed in the United States and Europe have become key ... -
Hematopoietic Cell Transplantation-Specific Comorbidity Index Predicts Morbidity and Mortality in Autologous Stem Cell Transplantation.
(Elsevier, 2017-10-01)The hematopoietic cell transplantation-specific comorbidity index (HCT-CI) score is a useful tool to assess the risk for nonrelapse mortality (NRM) after allogeneic hematopoietic stem cell transplantation. Although the ... -
Predictive models for recurrence risk of hepatocellular carcinoma after liver transplantation: Still an unmet need.
(Wiley, 2017-05-01)Recurrence of hepatocellular carcinoma (HCC) after liver transplanta-tion (LT) is a frightening issue. It is considered a systemic advanced stage with poor survival rate from the time of its diagnosis, with few therapeutic ... -
Liver disease and dyslipidemia as a manifestation of lysosomal acid lipase deficiency (LAL-D). Clinical and diagnostic aspects, and a new treatment. An update.
(Sociedad Argentina de Pediatría., 2017-06-01)Lysosomal acid lipase deficiency (LAL-D) is still a little recognized genetic disease with significant morbidity and mortality in children and adults. This document provides guidance on when to suspect LAL-D and how to ... -
Liver transplantation for hepatocellular carcinoma: evaluation of the alpha-fetoprotein model in a multicenter cohort from Latin America.
(Wiley, 2016-11-01)BACKGROUND & AIMS: The French alpha-fetoprotein (AFP) model has recently shown superior results compared to Milan criteria (MC) for prediction of hepatocellular carcinoma (HCC) recurrence after liver transplantation (LT) ... -
The Latin American DILI Registry Experience: A Successful Ongoing Collaborative Strategic Initiative.
(MDPI, 2016-02-25)Drug induced liver injury (DILI) is a rare but well recognized serious adverse reaction. Pre-marketing studies may not detect liver injury, and DILI becomes very often apparent after the drug is launched to the market. ... -
Encuentro sobre educación de cuidado paliativo en Latinoamérica. Recomendaciones sobre enseñanza en el pregrado y en el primer nivel de atención de salud
(Elsevier Espana,, 2016-01-01)En muchos países de Latinoamérica el desarrollo del cuidado paliativo es aún incipiente. Una razón fundamental es que la formación de los profesionales de la salud en esta disciplina, aunque intensa y progresivamente ... -
Medical students' palliative care education in a Latin American university: a three-year experience at Austral University in Buenos Aires, Argentina.
(Mary Ann Liebert, Inc, 2014-10-10)BACKGROUND: The School of Medicine of Austral University incorporated palliative care as an elective in undergraduate medicine curriculum during 2010. OBJECTIVE: We analyzed the experience and results after 3 years ... -
Isolated Intrapulmonary Vascular Dilatations and the Risk of Developing Hepatopulmonary Syndrome in Liver Transplant Candidates.
(Elsevier, 2017-08-01)BACKGROUND: The natural history of intrapulmonary vascular dilations (IPVD) and their impact on patient outcomes in the setting of portal hypertension has only been described in small series. AIMS: To assess the ... -
Ombitasvir/paritaprevir/ritonavir/dasabuvir ± ribavirin is safe and effective in HCV-infected patients in a real-life cohort from Latin America.
(Wiley, 2017-09-01)Information about the use of ombitasvir/paritaprevir/ritonavir/dasabuvir ± ribavirin (OBV/PTV/r/DSV ± RBV) in real-clinical practice in Latin America is scarce. We aimed to confirm safety and effectiveness of OBV/PTV/r/DSV ± RBV ... -
Combined rasagiline and antidepressant use in Parkinson disease in the ADAGIO study: effects on nonmotor symptoms and tolerability.
(JAMA Neurology, 2015-01-01)IMPORTANCE: Depression, cognitive impairment, and other nonmotor symptoms (NMSs) are common early in Parkinson disease (PD) and may be in part due to disease-related dopamine deficiency. Many patients with PD are treated ... -
Reacción anafiláctica fatal por Basiliximab
(Asociación Regional de Diálisis y Trasplantes Renales de Capital Federal y Provincia de Buenos Aires, 2015-09-25)El Basiliximab es un anticuerpo monoclonal ampliamente utilizado en trasplante renal para la inducción de inmunosupresión. Su introducción ha disminuido la incidencia de rechazo agudo en el primer año postrasplante renal ...