RSS 1.0Investigación Aplicada
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Argentine consensus recommendations for lung cancer screening programmes: a RAND/UCLA-modified Delphi study
(BMJOpen, 2023-02-03)Background: Lung cancer (LC) screening improves LC survival; the best screening method in terms of improving survival is low-dose CT (LDCT), outpacing chest X-ray and sputum cytology. Methods: A consensus of experts in ... -
El valor de la paternidad
(cuadernos para la formación sacerdotal permanente, 2021-10)Padres Se ha dicho que “hay un quiebre social en el proceso de hacer humanos a los humanos”; este punto es clave, es la base de cualquier análisis de la paternidad. En su sentido mas genérico, educar es mejorar al hombre4. -
IMT504 blocks allodynia in rats with spared nerve injury by promoting the migration of mesenchymal stem cells and by favoring an anti-inflammatory milieu at the injure nerve
(International Association for the Study of Pain, 2021-09)IMT504, a noncoding, non-CpG oligodeoxynucleotide, modulates pain-like behavior in rats undergoing peripheral nerve injury, through mechanisms that remain poorly characterized. Here, we chose the spared nerve injury model ... -
Maritornes y la genética
(Archivos Argentinos de Pediatría, 2020)Maritornes es una de las figuras femeninas creadas por Cervantes en El Quijote. Aparece en varios capítulos de la primera parte, y es más importante su protagonismo en los capítulosXVI y XLIII. En la primera aparición ... -
15. Diabetes Care in the Hospital: Standards of Medical Care in Diabetes-2021
(Diabetes Care, 2021-01-01)The American Diabetes Association (ADA) "Standards of Medical Care in Diabetes" includes the ADA's current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment ... -
Ilex paraguariensis extracts and its polyphenols prevent oxidative damage and senescence of human retinal pigment epithelium cells
(Elsevier Ltd. All rights reserved, 2020-04-01)Abstract Aged-related macular degeneration (AMD), a prevalent chronic disease leading to blindness, is associated with oxidative damage of the retinal pigment epithelium (RPE). Ilex paraguariensis (yerba mate, YM), widely ... -
Elucidating the mechanism of action of alpha-1-antitrypsin using retinal pigment epithelium cells exposed to high glucose. Potential use in diabetic retinopathy
(Potilinski et a, 2020-02-07)Abstract Background: Alpha-1-antitrypsin is a protein involved in avoidance of different processes that are seen in diabetic retinopathy pathogenesis. These processes include apoptosis, extracellular matrix remodeling and ... -
Prenatal genetic considerations in congenital ventriculomegaly and hydrocephalus
(Springer, 2020-08-31)Abstract Background: Fetal ventriculomegaly (VM) is a frequent finding in prenatal ultrasound. Rather than a proper diagnosis, VM is a sonographic sign, making prenatal counseling a complex and challenging undertaking. ... -
Renal Transplantation in Patients Older Than 60 Years With High Comorbidity. Is There a Survival Benefit? A Multicenter Study in Argentina
(Wolters Kluwer, 2020-08-01)Abstract Background: The impact of renal transplantation (RT) in the elderly with many comorbid conditions is a matter of concern. The aim of our study was to assess the impact of RT on the survival of patients older than ... -
Glucocorticoid and progesterone mechanisms in photoreceptor survival
(Elsevier B.V. ScienceDirect, 2020-01-01)Abstract Death of retinal photoreceptors is the basis of prevalent blinding diseases. Since steroids might have a therapeutic role in retinal degenerations, we compared the protective effects of dexamethasone and progesterone ... -
Sarcoidosis al descubierto: Lo que deberíamos informar en las imágenes torácicas.
(Sociedad Argentina de Radiología, 2019-07-25)La sarcoidosis es una enfermedad granulomatosa no caseificante, multisistémica, de causa desconocida, que compromete al pulmón y a los ganglios linfáticos mediastinales entre el 90 y el 95% de los casos. También puede ... -
Children admitted to PICU after hematopoietic stem cell transplantation: A predictive model of mortality.
(Torres et al., 2019-08-16)Abstract Introduction: Hematopoietic stem cell transplantation (HSCT) in children is associated with severe complications that need admission to critical care units. Mortality in this group of patients remains high with ... -
A Comprensive study of epigenetic alterations in hepatocellular carcicoma identifies potencial therapeutic targets.
(Elsevier B.V. All rights reserved, 2019-07-01)Abstract Background & aims: A causal link has recently been established between epigenetic alterations and hepatocarcinogenesis, indicating that epigenetic inhibition may have therapeutic potential. We aimed to identify ... -
A different gut microbiome linked to inflammation found in cirrhotic patients with and without hepatocellular carcinoma.
(Elsevier B.V. ScienceDirect, 2019-04-15)Abstract Introduction and aim: A pro-oncogenic intestinal microbiome was observed in murine models; however, no specific microbiome in patients with hepatocellular carcinoma (HCC) has been reported. We aimed to compare ... -
Hypotonic and isotonic intravenous maintenance fluids in hospitalized controlled trial.
(BMJ Publishing Group, 2019-05-09)Abstract Objective: To compare the changes in serum sodium and acid/base status in patients receiving hypotonic and isotonic solutions. Design: A randomised, controlled and double-blind clinical trial. Setting: ... -
Looking for the Best Model to Predict Hepatocellular Carcinoma Recurrence After Liver Transplantation in Latin America.
(the American Association for the Study of Liver Diseases, 2019-02-01) -
Hepatocellular carcinoma in Latin America: Diagnosis and treatment challenges
(Baishideng Publishing Group, 2018-10-07)Abstract Latin America, a region with a population greater than 600000000 individuals, is well known due to its wide geographic, socio-cultural and economic heterogeneity. Access to health care remains as the main barrier ... -
Fatty liver disease, an emerging etiology of hepatocellular carcinoma in Argentina
(Baishideng Publishing Group Inc, 2018-01-27)Abstract Aim: To investigate any changing trends in the etiologies of hepatocellular carcinoma (HCC) in Argentina during the last years. Methods: A longitudinal cohort study was conducted by 14 regional hospitals ... -
Incidence, risk factors, and outcomes related with neurological events after liver transplantation in adult and pediatric recipients.
(John Wiley & Sons A/S. Published by John Wiley & Sons Ltd, 2018-02-07)Abstract Controversy exists whether NE after LT are more frequently observed in children or adults. We aimed to compare the incidence and outcomes for NE after LT in pediatric and adult recipients. A single-center cohort ... -
Treatment with direct-acting antivirals for HCV decreases but does not eliminate the risk of hepatocellular carcinoma.
(Wiley, 2019-01-13)Abstract Background & Aims: Data from Europe and North America have been published re‐ garding the risk of developing hepatocellular carcinoma (HCC) after treatment with direct antiviral agents (DAA). We proposed to ...