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Chronic hepatitis C and chronic kidney disease: Advances, limitations and unchartered territories
(Wiley, 2017-01-20)
Over the past few years, treatment options for chronic hepatitis C virus (HCV) infection have evolved dramatically. The current approved interferon-free direct-acting antiviral (DAA) regimens have been shown to be safe and ...
Loss of dystrophin is associated with increased myocardial stiffness in a model of left ventricular hypertrophy.
(Springer, 2017-03-18)
Transition from compensated to decompensated left ventricular hypertrophy (LVH) is accompanied by functional and structural changes. Here, the aim was to evaluate dystrophin expression in murine models and human subjects ...
Biomarker-driven phenotyping in Parkinson's disease: A translational missing link in disease-modifying clinical trials.
(Wiley, 2017-02-24)
Past clinical trials of putative neuroprotective therapies have targeted PD as a single pathogenic disease entity. From an Oslerian clinicopathological perspective, the wide complexity of PD converges into Lewy bodies and ...
The current status of patient safety in Argentina: Cross sectional study
(Archivos argentinos de pediatria, 2017-02-01)
Background. Patient safety is a priority for
healthcare organizations. For the PRONAP´s
2013 final exam, the Quality & Patient Safety
Subcommittee and the PRONAP managers
designed a survey to be answered by ...
Response to "Comments on 'The Effects of Fat Harvesting and Preparation, Air Exposure, Obesity, and Stem Cell Enrichment on Adipocyte Viability Prior to Graft Transplantation'".
(Oxford University Press, 2017-04-01)
Response to “Comments on ‘The Effects of Fat Harvesting and Preparation, Air Exposure, Obesity, and Stem Cell Enrichment on Adipocyte Viability Prior to Graft Transplantation’”
The Process of Lipid Storage in Insect Oocytes: The Involvement of β-Chain of ATP Synthase in Lipophorin-Mediated Lipid Transfer in the Chagas' Disease Vector Panstrongylus Megistus (Hemiptera: Reduviidae)
(Elsevier B.V. ScienceDirect, 2017-01-01)
Lipophorin is the main lipoprotein in the hemolymph of insects. During vitellogenesis, lipophorin delivers its hydrophobic cargo to developing oocytes by its binding to non-endocytic receptors at the plasma membrane of the ...
International variations in application of the best-interest standard across the age spectrum.
(Springer Nature [academic journals on nature.com], 2017-02-01)
OBJECTIVE:
Ethically and legally, assertions that resuscitation is in a patient's best interest should be inversely correlated with willingness to forego intensive care (and accept comfort care) at the surrogate's request. ...
Early ciliary and prominin-1 dysfunctions precede neurogenesis impairment in a mouse model of type 2 diabetes.
(Elsevier Inc. All rights reserved., 2017-12-01)
Diabetes mellitus (DM) is reaching epidemic conditions worldwide and increases the risk for cognition impairment and dementia. Here, we postulated that progenitors in adult neurogenic niches might be particularly vulnerable. ...
Hyponatremia and fractures: should hyponatremia be further studied as a potential biochemical risk factor to be included in FRAX algorithms?
(Springer, 2017-01-10)
The Fracture Risk Assessment Tool (FRAX®) was developed by the WHO Collaborating Centre for metabolic bone diseases to evaluate fracture risk of patients. It is based on patient models that integrate the risk associated ...
Physical Activity Among Organ Recipients: Data Collected From the Latin American Transplant Games.
(Elsevier, 2017-03-01)
Background
Cardiovascular complications after transplantation are an important cause of non–transplant-related deaths. Depression and anxiety are not unusual among organ recipients. Physical activity reduces cardiovascular ...