Browsing Investigación Aplicada by Title
Now showing items 21-40 of 225
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Chronic hepatitis C and chronic kidney disease: Advances, limitations and unchartered territories.
(Wiley, 2017-06-01)Over the past few years, treatment options for chronic hepatitis C virus (HCV) infection have evolved dramatically. The current approved interferon-free direct-acting antiviral (DAA) regimens have been shown to be safe and ... -
Chronic hyperprolactinemia evoked by disruption of lactotrope dopamine D2 receptors impacts on liver and adipocyte genes related to glucose and insulin balance.
(American Physiological Society, 2016-11-01)We studied the impact of high prolactin titers on liver and adipocyte gene expression related to glucose and insulin homeostasis in correlation with obesity onset. To that end we used mutant female mice that selectively ... -
Clinical epidemiology of acute hepatitis C in South America.
(Wiley, 2016-06)There is scarce data pertaining to acute hepatitis C (aHC) infection in South America. We aimed to describe clinical characteristics and evolution of aHC in a South American cohort. A retrospective survey was conducted at ... -
Combined rasagiline and antidepressant use in Parkinson disease in the ADAGIO study: effects on nonmotor symptoms and tolerability.
(JAMA Neurology, 2015-01-01)IMPORTANCE: Depression, cognitive impairment, and other nonmotor symptoms (NMSs) are common early in Parkinson disease (PD) and may be in part due to disease-related dopamine deficiency. Many patients with PD are treated ... -
A Comprensive study of epigenetic alterations in hepatocellular carcicoma identifies potencial therapeutic targets.
(Elsevier B.V. All rights reserved, 2019-07-01)Abstract Background & aims: A causal link has recently been established between epigenetic alterations and hepatocarcinogenesis, indicating that epigenetic inhibition may have therapeutic potential. We aimed to identify ... -
Considerations about the infant safe sleep: Executive summary
(Arch Argent Pediatr., 2015-06-01)Arch Argent Pediatr. 2015 Jun;113(3):285-7. doi: 10.5546/aap.2015.285. [Considerations about the infant safe sleep: Executive summary]. [Article in Spanish] Grupo de Trabajo en Muerte Súbita e Inesperada del Lactante, ... -
Corneal Neovascularization: A Combined Approach of Bevacizumab and Suramin Showed Increased Antiangiogenic Effect Through Downregulation of BFGF and P2X2
(Current Eye Research, 2017-12-21)ABSTRACT Purpose: The objective is to analyze the antiangiogenic mechanism of suramab, a pharmaceutical compound of bevacizumab and suramin, in a rabbit model of corneal angiogenesis. Material and Methods: Corneal ... -
Cross-Cultural Adaptation and Psychometric Evaluation of a Second Victim Experience and Support Tool (SVEST)
(Wolters Kluwer Health, Inc., 2018-05-03)Abstract Introduction: The second victim is defined as the health professionals who commit an error and are traumatized by the event manifesting psychological, cognitive, and/or physical reactions that have a personal ... -
The current status of patient safety in Argentina: Cross sectional study
(Archivos argentinos de pediatria, 2017-02-01)Background. Patient safety is a priority for healthcare organizations. For the PRONAP´s 2013 final exam, the Quality & Patient Safety Subcommittee and the PRONAP managers designed a survey to be answered by ... -
The damping effect of cement as a potential mitigation factor of squeaking in ceramic-on-ceramic total hip arthroplasty
(British Editorial Society of Bone and Joint Surgery, 2016-11-03)Objectives Studies reporting specifically on squeaking in total hip arthroplasty have focused on cementless, and not on hybrid, fixation. We hypothesised that the cement mantle of the femur might have a damping effect on ... -
Definition, aims, and implementation of GA2 LEN/HAEi Angioedema Centers of Reference and Excellence
(Wiley, 2020-08)Definition, aims, and implementation of GA2 LEN/HAEi Angioedema Centers of Reference and Excellence To the Editor, GA2 LEN, the Global Allergy and Asthma European Network, and HAE international (HAEi), the global ... -
Developing multicenter consortia in liver disease in Latin America: Challenges and opportunities.
(Wiley, 2017-06-07)The development of consortia has been useful for exploring challenging scenarios and uncharted territories in liver disease treatments. Several consortia already developed in the United States and Europe have become key ... -
Diabetes mellitus, maternal adiposity, and insulin-dependent gestational diabetes are associated with COVID-19 in pregnancy: the INTERCOVID study
(Elsevier, 2022-07)Abstract Background: Among nonpregnant individuals, diabetes mellitus and high body mass index increase the risk of COVID-19 and its severity. Objective: This study aimed to determine whether diabetes mellitus and high ... -
A different gut microbiome linked to inflammation found in cirrhotic patients with and without hepatocellular carcinoma
(Elsevier, 2019-04-15)Abstract Introduction and aim: A pro-oncogenic intestinal microbiome was observed in murine models; however, no specific microbiome in patients with hepatocellular carcinoma (HCC) has been reported. We aimed to compare ... -
A different gut microbiome linked to inflammation found in cirrhotic patients with and without hepatocellular carcinoma.
(Elsevier B.V. ScienceDirect, 2019-04-15)Abstract Introduction and aim: A pro-oncogenic intestinal microbiome was observed in murine models; however, no specific microbiome in patients with hepatocellular carcinoma (HCC) has been reported. We aimed to compare ... -
Direct-acting antiviral treatment failure in genotype 2 hepatitis C chronic infection
(Wiley, 2021-02)Comment J Viral Hepat . 2021 Feb;28(2):446-447. doi: 10.1111/jvh.13433. Epub 2020 Nov 18. Direct-acting antiviral treatment failure in genotype 2 hepatitis C chronic infection Ezequiel Ridruejo 1 2 3, Federico Piñero 2 ... -
Disease Progression in Patients With Hepatitis C Virus Infection Treated With Direct-Acting Antiviral Agents.
(Elsevier, 2020-10)Abstract Background & aims: Little is known about how a sustained virologic response (SVR) to treatment of hepatitis C virus infection with direct-acting antivirals (DAAs) affects patient mortality and development of new ... -
Dorsal root ganglion neurons and tyrosine hydroxylase--an intriguing association with implications for sensation and pain.
(International Association for the Study of Pain, 2016-02-01)Tyrosine hydroxylase (TH) is a rate-limiting enzyme broadly expressed in noradrenergic and dopaminergic neurons in the central nervous system [57,70]. TH is also expressed by peripheral sympathetic neurons [98] as well ... -
Dropout rate from the liver transplant waiting list because of hepatocellular carcinoma progression in hepatitis C virus-infected patients treated with direct-acting antivirals.
(Wiley, 2017-10-01)We have read with interest the article recently pub-lished by Zanetto et al. inLiver Transplantationregarding the effect on radiologic progression of hepa-tocellular carcinoma (HCC) after the treatment withdirect-acting ... -
Drug-induced liver injury: A management position paper from the Latin American Association for Study of the liver
(Elsevier, 2021-09)Abstract Idiosyncratic drug-induced liver injury (DILI) caused by xenobiotics (drugs, herbals and dietary supplements) is an uncommon cause of liver disease presenting with a wide range of phenotypes and disease severity, ...