Browsing Investigación Aplicada by Title
Now showing items 139-158 of 225
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Ombitasvir / paritaprevir / ritonavir / dasabuvir ± ribavirina es segura y efectiva en el HCV - infectados pacientes en una vida real cohorte de América Latina .
(Wiley, 2017-03-29)Information about the use of ombitasvir/paritaprevir/ritonavir/dasabuvir ± ribavirin (OBV/PTV/r/DSV ± RBV) in real-clinical practice in Latin America is scarce. We aimed to confirm safety and effectiveness of OBV/PTV/r/DSV ± RBV ... -
Ombitasvir/paritaprevir/ritonavir/dasabuvir ± ribavirin is safe and effective in HCV-infected patients in a real-life cohort from Latin America.
(Wiley, 2017-09-01)Information about the use of ombitasvir/paritaprevir/ritonavir/dasabuvir ± ribavirin (OBV/PTV/r/DSV ± RBV) in real-clinical practice in Latin America is scarce. We aimed to confirm safety and effectiveness of OBV/PTV/r/DSV ± RBV ... -
Open intrauterine repair of spina bifida aperta: Historical aspects, current availability, and clinical outcomes from the Latin American Spina Bifida Consortium
(Wiley, 2021-07)Abstract Objective: To determine the historical aspects, current availability, and clinical outcomes of open intrauterine repair of spina bifida aperta (IRSBA) in Spanish-speaking Latin American countries. Methods: ... -
Outbreak of hepatitis A in a post-vaccination era: High rate of co-infection with sexually transmitted diseases
(Elsevier, 2020-11)Abstract Introduction and objectives: After hepatitis A (HAV) mandatory immunization in 2005 in Argentina, the incidence of HAV declined drastically. However, several new autochthonous cases of HAV have been reported since ... -
Outcome of COVID-19 in Patients With Autoimmune Hepatitis: An International Multicenter Study
(Lippincott, Williams & Wilkins, 2021-06)Abstract Background and aims: Data regarding outcome of COVID-19 in patients with autoimmune hepatitis (AIH) are lacking. Approach and results: We performed a retrospective study on patients with AIH and COVID-19 from ... -
Outcomes of patients with non-small cell lung cancer and poor performance status treated with immune checkpoint inhibitors in the real-world setting
(Springer, 2021-06)Abstract Background: Immune-checkpoint inhibitors (ICIs) are standard treatments for metastatic non-small cell lung cancer (NSCLC). Patients with poor performance status (PS) are underrepresented in clinical trials. We ... -
Outcomes of surgical treatment for isolated adrenal metastasis from non-small cell lung cancer
(Ecancermedicalscience, 2021-11)Abstract Objective: Long-term survival of patients who undergo surgical resection of isolated adrenal metastasis instead of nonsurgical treatment has shown higher values than those described for stage IVA. The primary ... -
Oxidative stress-induced premature senescence dysregulates VEGF and CFH expression in retinal pigment epithelial cells: Implications for Age-related Macular Degeneration
(Elsevier B.V. ScienceDirect, 2016-04-01)Oxidative stress has a critical role in the pathogenesis of Age-related Macular Degeneration (AMD), a multifactorial disease that includes age, gene variants of complement regulatory proteins and smoking as the main risk ... -
Pediatric KT in children up to 15 kg: A single-center experience
(Wiley, 2021-12)Abstract Background: KT is the preferred treatment for ESRD in pediatrics. However, it may be challenging in those weighing ≤15 kg with potential complications that impact on morbidity and graft loss. Methods: This ... -
Pediatric Oncology Nursing Research in Low- and Middle-Income Countries: Exemplars from Three Regions
(Elsevier, 2021-06)Abstract Objective: This study examined the status of pediatric oncology nursing research in three low- and middle-income countries (LMICs) as examples across three World Health Organization regions: East Africa, Eastern ... -
Physical Activity Among Organ Recipients: Data Collected From the Latin American Transplant Games.
(Elsevier, 2017-03-01)Background Cardiovascular complications after transplantation are an important cause of non–transplant-related deaths. Depression and anxiety are not unusual among organ recipients. Physical activity reduces cardiovascular ... -
Pluripotent Nontumorigenic Adipose Tissue-Derived Muse Cells have Immunomodulatory Capacity Mediated by Transforming Growth Factor-β1
(Wiley Open Access, 2017-01-01)Adult mesenchymal stromal cell-based interventions have shown promising results in a broad range of diseases. However, their use has faced limited effectiveness owing to the low survival rates and susceptibility to ... -
Possible neuroprotective role of P2X2 in the retina of diabetic rats.
(Springer Nature, 2018-04-12)Abstract Background: Purinergic receptors are expressed in diferent tissues including the retina. These receptors are involved in processes like cell growth, proliferation, activation and survival. ATP is the major ... -
Post-transplant cyclophosphamide demonstrates lower non-relapse mortality and better graft-versus-host disease/relapse-free survival compared with antithymocyte globulin in unrelated donor hematopoietic stem cell transplantation. A single-center experience
(Springer Nature, 2021-04)Post-transplant cyclophosphamide demonstrates lower non-relapse mortality and better graft-versus-host disease/relapse-free survival compared with antithymocyte globulin in unrelated donor hematopoietic stem cell ... -
Practice-Changing Use of the 21-Gene Test for the Management of Patients With Early-Stage Breast Cancer in Latin America
(American Society of Clinical Oncology, 2021-08)Abstract Purpose: We present a physician survey of the impact of 21-gene Breast Recurrence Score test results on treatment decisions in clinical practice in Latin America. Methods: This prospective survey enrolled ... -
Predicting Mortality after Autologous Transplant: Development of a Novel Risk Score
(Elsevier, 2020-10)Abstract There have been several efforts to predict mortality after autologous stem cell transplantation (ASCT), such as the hematopoietic cell transplant-comorbidity index (HCT-CI), described for allogeneic stem cell ... -
Predictive models for recurrence risk of hepatocellular carcinoma after liver transplantation: Still an unmet need.
(Wiley, 2017-05-01)Recurrence of hepatocellular carcinoma (HCC) after liver transplanta-tion (LT) is a frightening issue. It is considered a systemic advanced stage with poor survival rate from the time of its diagnosis, with few therapeutic ... -
Preeclampsia and COVID-19: results from the INTERCOVID prospective longitudinal study
(Elsevier, 2021-09)Abstract Background: It is unclear whether the suggested link between COVID-19 during pregnancy and preeclampsia is an independent association or if these are caused by common risk factors. Objective: This study aimed ... -
Prenatal genetic considerations in congenital ventriculomegaly and hydrocephalus
(Springer, 2020-08-31)Abstract Background: Fetal ventriculomegaly (VM) is a frequent finding in prenatal ultrasound. Rather than a proper diagnosis, VM is a sonographic sign, making prenatal counseling a complex and challenging undertaking. ... -
Prenatal genetic considerations in congenital ventriculomegaly and hydrocephalus.
(Springer, 2020-08)Abstract Background: Fetal ventriculomegaly (VM) is a frequent finding in prenatal ultrasound. Rather than a proper diagnosis, VM is a sonographic sign, making prenatal counseling a complex and challenging undertaking. ...