Browsing Investigación Aplicada by Title
Now showing items 203-222 of 225
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Targeting ADCC: A different approach to HER2 breast cancer in the immunotherapy era
(Elsevier, 2021-12)Abstract The clinical outcome of patients with human epidermal growth factor receptor 2 (HER2) amplified breast carcinoma (BC) has improved with the development of anti-HER2 targeted therapies. However, patients can ... -
The impact of hydroxychloroquine on obstetric outcomes in refractory obstetric antiphospholipid syndrome
(Elsevier, 2021-10)Abstract Background: The use of low-dose aspirin (LDA) and heparin has improved pregnancy outcomes in women with antiphospholipid syndrome (APS). However, 20-30% still have adverse outcomes despite treatment. Recent ... -
The Latin American Association for the Study of the Liver (ALEH) position statement on the redefinition of fatty liver disease
(Elsevier, 2021-01)Abstract The Latin American Association for the Study of the Liver (Asociación Latinoamericana para el Estudio del Hígado; ALEH) represents liver professionals in Latin America with the mission of promoting liver health ... -
The liver in times of COVID-19: What hepatologists should know
(Elsevier, 2020-07)Abstract The ongoing pandemic of coronavirus disease 2019 (COVID-19) pandemic poses a serious threat to healthcare systems globally. Information regarding how the infection affects the liver and relevance of pre-existing ... -
The prevalence of migraine in Argentina: A reappraisal
(SAGE Publications, 2021-06)Abstract Background: Argentina has one of the largest territories in the world, which spreads over a lengthy latitudinal span. Its population is mainly composed of a mixture of South American natives and the descendants ... -
The tale of TILs in breast cancer: A report from The International Immuno-Oncology Biomarker Working Group
(Nature Research, 2021-12)Abstract The advent of immune-checkpoint inhibitors (ICI) in modern oncology has significantly improved survival in several cancer settings. A subgroup of women with breast cancer (BC) has immunogenic infiltration of ... -
The unfinished work of neonatal very low birthweight infants quality improvement: Improving outcomes at a continental level in South America
(Elsevier, 2021-02)Abstract Neonatal mortality rate varies between 4.2 and 18.6 per thousand by country in South America. There is little information regarding the outcomes of very low birth weight infants in the region and mortality rates ... -
Tolvaptan in Later-Stage Autosomal Dominant Polycystic Kidney Disease.
(Massachusetts Medical Society, 2017-11-16)BACKGROUND: In a previous trial involving patients with early autosomal dominant polycystic kidney disease (ADPKD; estimated creatinine clearance, ≥60 ml per minute), the vasopressin V2-receptor antagonist tolvaptan slowed ... -
Transforming growth factor-β1 functional polymorphisms in myeloablative sibling hematopoietic stem cell transplantation
(Springer Nature [academic journals on nature.com], 2017-05-01)Hematopoietic stem cell transplantation (HSCT) with sibling donors (s.d.) is a life-saving intervention for patients with hematological malignancies. Numerous genetic factors have a role in transplant outcome. Several ... -
Treatment of Fabry's Disease with the Pharmacologic Chaperone Migalastat.
(Massachusetts Medical Society, 2016-08-11)BACKGROUND: Fabry's disease, an X-linked disorder of lysosomal α-galactosidase deficiency, leads to substrate accumulation in multiple organs. Migalastat, an oral pharmacologic chaperone, stabilizes specific mutant forms ... -
Treatment of hepatitis C virus infection with new direct-acting antivirals agents in pediatrics. Case report
(Archivos Argentinos de Pediatría, 2021-08)Abstract in English, Spanish Hepatitis C virus infection in children occurs mainly through vertical transmission. The natural history at this age consists in a high rate of spontaneous clearance, asymptomatic infection, ... -
Treatment of Minimally Invasive Hallux Valgus Surgery Complications
(Wolters Kluwer, 2017-03-01)Percutaneous foot surgery is a surgical method of treating various bone and soft-tissue disorders of the foot. In hallux valgus pathology, it is called minimal incision surgery, and is another method to treat this disorder. ... -
Treatment with direct-acting antivirals for HCV decreases but does not eliminate the risk of hepatocellular carcinoma.
(Wiley, 2019-01-13)Abstract Background & Aims: Data from Europe and North America have been published re‐ garding the risk of developing hepatocellular carcinoma (HCC) after treatment with direct antiviral agents (DAA). We proposed to ... -
Trial eligibility in advanced hepatocellular carcinoma: Does it support clinical practice in underrepresented subgroups?
(Baishideng Publishing Group, 2021-06)Abstract Although hepatocellular carcinoma is considered a highly lethal malignancy, recent therapeutic advances have been achieved during the last 10 years. This scenario resulted in an unprecedented improvement in ... -
Two Synchronous Neonatal Tumors: An Extremely Rare Case
(Hindawi, 2021-04)Abstract We report a case of a newborn with two synchronous tumors-sialoblastoma and hepatoblastoma-diagnosed at 20 weeks of gestation by magnetic resonance imaging (MRI) and ultrasonography (US). The aim of this study ... -
Uncovering the in vivo source of adult neural crest stem cells
(Mary Ann Liebert, Inc, 2017-03-01)Some late embryonic and adult postmigratory neural crest-derived cells (NCDCs) from diverse tissues were shown to grow as multipotent neurospheres. Neural crest stem cells (NCSCs) contained in these spheres were found to ... -
Uncovering the in vivo source of adult neural crest stem cells.
(Mary Ann Liebert, 2017-03-01)Some late embryonic and adult postmigratory neural crest-derived cells (NCDCs) from diverse tissues were shown to grow as multipotent neurospheres. Neural crest stem cells (NCSCs) contained in these spheres were found to ... -
Update on the epidemiology of carbapenemases in Latin America and the Caribbean
(Taylor and Francis Group, 2021-02)Abstract Introduction: Carbapenemases are β-lactamases able to hydrolyze a wide range of β-lactam antibiotics, including carbapenems. Carbapenemase production in Enterobacterales, Pseudomonas aeruginosa, and Acinetobacter ... -
Upper Limb Lengthening in Achondroplasia Using Unilateral External Fixation
(Lippincott, Williams & Wilkins, 2021-04)Abstract Purpose: The purpose of this study was to analyze the long-term results of humeral lengthening in achondroplastic patients and make suggestions on the most appropriate surgical technique to improve patient ... -
Utility of PET-CT in non-small cell lung cancer clinical stage IB-IIA according to AJCC 8th edition staging system: an alternative to invasive mediastinal staging?
(Ecancermedicalscience, 2021-06)Abstract Objective: Mediastinal nodal staging in lung cancer is essential to determine treatment strategy and prognosis. There are controversies as to whether a mediastinal negative result in PET-CT may spare the invasive ...