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Intrathecal Administration of an Anti-nociceptive Non-CpG Oligodeoxynucleotide Reduces Glial Activation and Central Sensitization
(Springer, 2021-12)
Abstract
Inflammatory pain associates with spinal glial activation and central sensitization. Systemic administration of IMT504, a non-CpG oligodeoxynucleotide originally designed as an immunomodulator, exerts remarkable ...
CSIS: Proposal for a New Combined Screening Interpretation Score for Patients with Mild Cognitive Impairment
(Taylor and Francis Group, 2021-04)
Abstract
Introduction: It is essential to have sensitive, economical and quick cognitive screening tools for early detection of Mild Cognitive Impairment (MCI). The objective of the present study was to assess a new way ...
Post-transplant cyclophosphamide demonstrates lower non-relapse mortality and better graft-versus-host disease/relapse-free survival compared with antithymocyte globulin in unrelated donor hematopoietic stem cell transplantation. A single-center experience
(Springer Nature, 2021-04)
Post-transplant cyclophosphamide demonstrates lower non-relapse mortality and better graft-versus-host disease/relapse-free survival compared with antithymocyte globulin in unrelated donor hematopoietic stem cell ...
Children admitted to a pediatric intensive care unit after hematopoietic stem cell transplantation: Analysis of survival and predictors of mortality
(Sociedad Argentina de Pediatría, 2021-08)
Abstract in English, Spanish
Introduction: Hematopoietic stem cell transplantation (HSCT) in children is a procedure that is not exempt of severe complications. Admission to the pediatric intensive care unit (PICU) is ...
Controlling cholesterol entry into mitochondria, a key step for hepatocarcinogenesis in non-alcoholic steatohepatitis-related hepatocellular carcinoma
(AME Publishing, 2021-12)
Hepatocellular carcinoma (HCC) is the sixth most common cancer and the second leading cause of cancer-related death worldwide (1). Unfortunately, the incidence and mortality of HCC are increasing steadily in formerly ...
Two Synchronous Neonatal Tumors: An Extremely Rare Case
(Hindawi, 2021-04)
Abstract
We report a case of a newborn with two synchronous tumors-sialoblastoma and hepatoblastoma-diagnosed at 20 weeks of gestation by magnetic resonance imaging (MRI) and ultrasonography (US). The aim of this study ...
IMT504 Provides Analgesia by Modulating Cell Infiltrate and Inflammatory Milieu in a Chronic Pain Model
(Springer [Commercial Publisher], 2021-09)
Abstract
IMT504 is a non-CPG, non-coding synthetic oligodeoxinucleotide (ODN) with immunomodulatory properties and a novel inhibitory role in pain transmission, exerting long-lasting analgesic effects upon multiple systemic ...
Controversies during the COVID-19 pandemic
(Fundación Revista Medicina, 2021)
Abstract in English, Spanish
The COVID-19 pandemic has had an impact on public health and the global economy. The objective of this document was to update, according to the available evidence, the management of some basic ...
Galectin-1 and Galectin-3 Expression in Lesional Skin of Patients With Systemic Sclerosis-Association With Disease Severity
(Lippincott, Williams & Wilkins, 2021-12)
Abstract
Galectin-1 (Gal-1) and galectin-3 (Gal-3) are carbohydrate-binding proteins involved in normal processes, autoimmunity, and cancer. Increased serum Gal-3 levels in scleroderma were associated with active disease, ...
Outcome of COVID-19 in Patients With Autoimmune Hepatitis: An International Multicenter Study
(Lippincott, Williams & Wilkins, 2021-06)
Abstract
Background and aims: Data regarding outcome of COVID-19 in patients with autoimmune hepatitis (AIH) are lacking.
Approach and results: We performed a retrospective study on patients with AIH and COVID-19 from ...