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The tale of TILs in breast cancer: A report from The International Immuno-Oncology Biomarker Working Group
(Nature Research, 2021-12)
Abstract
The advent of immune-checkpoint inhibitors (ICI) in modern oncology has significantly improved survival in several cancer settings. A subgroup of women with breast cancer (BC) has immunogenic infiltration of ...
Magnetic resonance lymphangiography in group 1 paediatric pulmonary arterial hypertension
(Wiley Open Access, 2021-03)
Abstract
Pulmonary hypertension could have thoracic lymphatic abnormalities caused by right ventricular failure. Since there is no description of such abnormalities, the purpose of this study was to investigate them with ...
An Update on Hepatocellular Carcinoma in Chronic Kidney Disease
(MDPI [Commercial Publisher], 2021-07)
Abstract
Chronic kidney disease is a major public health issue globally and the risk of cancer (including HCC) is greater in patients on long-term dialysis and kidney transplant compared with the general population. ...
Simplified treatment of hepatitis C: another strategy to overcome the barriers to its elimination
(Medicina Buenos Aires, 2021-01)
Abstract in English, Spanish
The clinical management of hepatitis C virus (HCV) infection presents several challenges today. WHO's goal is to eliminate it by 2030. It is an ambitious goal and difficult to meet given the ...
Development of an Improved Guanidine-Based Rac1 Inhibitor with in vivo Activity against Non-Small Cell Lung Cancer
(Wiley, 2021-03)
Abstract
The Rho GTPase Rac1 is involved in the control of cytoskeleton reorganization and other fundamental cellular functions. Aberrant activity of Rac1 and its regulators is common in human cancer. In particular, ...
Clinical presentation and outcomes of the first patients with COVID-19 in Argentina: Results of 207079 cases from a national database
(Public Library of Science, 2021-02)
Abstract
Background: There is limited evidence on the clinical characteristics of SARS-CoV-2 infection in Latin America. We present findings from a nationwide study in Argentina.
Research question: What is disease ...
The prevalence of migraine in Argentina: A reappraisal
(SAGE Publications, 2021-06)
Abstract
Background: Argentina has one of the largest territories in the world, which spreads over a lengthy latitudinal span. Its population is mainly composed of a mixture of South American natives and the descendants ...
Pediatric Oncology Nursing Research in Low- and Middle-Income Countries: Exemplars from Three Regions
(Elsevier, 2021-06)
Abstract
Objective: This study examined the status of pediatric oncology nursing research in three low- and middle-income countries (LMICs) as examples across three World Health Organization regions: East Africa, Eastern ...
A familiar study on self-limited childhood epilepsy patients using hIPSC-derived neurons shows a bias towards immaturity at the morphological, electrophysiological and gene expression levels
(BMC, 2021-11-01)
Background: Self-limited Childhood Epilepsies are the most prevalent epileptic syndrome in children. Its pathogenesis is unknown. In this disease, symptoms resolve spontaneously in approximately 50% of patients when maturity ...
A Year of Living Dangerously: Challenges and Recommendations for Safely Performing Ophthalmic Surgery During the COVID-19 Pandemic, from Start to Finish
(Taylor and Francis Group [Commercial Publisher] Dove Press [Imprint], 2021-01-15)
Abstract
The COVID-19 pandemic has forced all nations to take an active role in infection control incorporating recommendations and measures to control viral dissemination. The epidemiological impact is very diverse and ...