Browsing Investigación Aplicada by Title
Now showing items 193-212 of 225
-
Spectrum and visual outcomes of Vogt-Koyanagi-Harada disease in Argentina.
(Press of International Journal of Ophthalmology, 2017-01-01)AIM: To review all cases of Vogt-Koyanagi-Harada (VKH) disease in an Inflammatory Eye Disease Service in Argentina and to describe the clinical profile and outcomes of treatment. METHODS: The records from patients ... -
Spinal neuropeptide expression and neuropathic behavior in the acute and chronic phases after spinal cord injury: Effects of progesterone administration.
(Elsevier Inc. All rights reserved., 2017-02)Patients with spinal cord injury (SCI) develop chronic pain that severely compromises their quality of life. We have previously reported that progesterone (PG), a neuroprotective steroid, could offer a promising therapeutic ... -
[Stiff skin syndrome in a pediatric patient: a therapeutic challenge. Clinical case]
(Archivos Argentinos de Pediatría, 2020-10)Abstract in English, Spanish Stiff skin syndrome is a chronic, rare sclerosing disorder that occurs in childhood, characterized by progressive induration of the skin that can cause thoracic restrictions and respiratory ... -
Succinate-CoA ligase deficiency due to mutations in SUCLA2 and SUCLG1: phenotype and genotype correlations in 71 patients.
(John Wiley & Sons, Inc. All rights reserved, 2016-03-01)BACKGROUND: The encephalomyopathic mtDNA depletion syndrome with methylmalonic aciduria is associated with deficiency of succinate-CoA ligase, caused by mutations in SUCLA2 or SUCLG1. We report here 25 new patients with ... -
Supporting Families After Traumatic Brain Injury, Is This a Way of Improving Results?
(Lippincott, Williams & Wilkins, 2016-07-01)Supporting Families After Traumatic Brain Injury, Is This a Way of Improving Results? -
Surgical technique for approaching chronic or persistent macular holes: Two case reports
(Elsevier, 2020-04)Abstract Purpose: To report the anatomic and functional outcomes of an innovative surgical technique for either chronic or persistent macular holes (MHs). Observations: A consecutive retrospective interventional case ... -
Surveillance for Hepatocellular Carcinoma: Does the Place Where Ultrasound Is Performed Impact Its Effectiveness?
(Springer Science+Business Media, LLC, part of Springer Nature, 2019-03-01)Abstract Background: Biannual ultrasound (US) is recommended as the clinical screening tool for hepatocellular carcinoma (HCC). The effectiveness of surveillance according to the place where US is performed has not been ... -
Sympathetic predominance is associated with impaired endothelial progenitor cells and tunneling nanotubes in controlled-hypertensive patients.
(American Physiological Society, 2014-05-23)Early endothelial progenitor cells (early EPC) and late EPC are involved in endothelial repair and can rescue damaged endothelial cells by transferring organelles through tunneling nanotubes (TNT). In rodents, EPC mobilization ... -
A systematic review of faculty development initiatives designed to enhance teaching effectiveness: A 10-year update: BEME Guide No. 40.
(Taylor & Francis, 2016-07-15)BACKGROUND: This review, which focused on faculty development initiatives designed to improve teaching effectiveness, synthesized findings related to intervention types, study characteristics, individual and organizational ... -
Systemic Transplantation of Bone Marrow Mononuclear Cells Promotes Axonal Regeneration and Analgesia in a Model of Wallerian Degeneration
(Lippincott, Williams & Wilkins, 2017-07)Background Reinnervation timing after nerve injury is critical for favorable axonal regeneration, remyelination, and clinical improvement. Considering bone marrow mononuclear cells (BMMC) are easily obtained and readily ... -
Targeting ADCC: A different approach to HER2 breast cancer in the immunotherapy era
(Elsevier, 2021-12)Abstract The clinical outcome of patients with human epidermal growth factor receptor 2 (HER2) amplified breast carcinoma (BC) has improved with the development of anti-HER2 targeted therapies. However, patients can ... -
The impact of hydroxychloroquine on obstetric outcomes in refractory obstetric antiphospholipid syndrome
(Elsevier, 2021-10)Abstract Background: The use of low-dose aspirin (LDA) and heparin has improved pregnancy outcomes in women with antiphospholipid syndrome (APS). However, 20-30% still have adverse outcomes despite treatment. Recent ... -
The Latin American Association for the Study of the Liver (ALEH) position statement on the redefinition of fatty liver disease
(Elsevier, 2021-01)Abstract The Latin American Association for the Study of the Liver (Asociación Latinoamericana para el Estudio del Hígado; ALEH) represents liver professionals in Latin America with the mission of promoting liver health ... -
The liver in times of COVID-19: What hepatologists should know
(Elsevier, 2020-07)Abstract The ongoing pandemic of coronavirus disease 2019 (COVID-19) pandemic poses a serious threat to healthcare systems globally. Information regarding how the infection affects the liver and relevance of pre-existing ... -
The prevalence of migraine in Argentina: A reappraisal
(SAGE Publications, 2021-06)Abstract Background: Argentina has one of the largest territories in the world, which spreads over a lengthy latitudinal span. Its population is mainly composed of a mixture of South American natives and the descendants ... -
The tale of TILs in breast cancer: A report from The International Immuno-Oncology Biomarker Working Group
(Nature Research, 2021-12)Abstract The advent of immune-checkpoint inhibitors (ICI) in modern oncology has significantly improved survival in several cancer settings. A subgroup of women with breast cancer (BC) has immunogenic infiltration of ... -
The unfinished work of neonatal very low birthweight infants quality improvement: Improving outcomes at a continental level in South America
(Elsevier, 2021-02)Abstract Neonatal mortality rate varies between 4.2 and 18.6 per thousand by country in South America. There is little information regarding the outcomes of very low birth weight infants in the region and mortality rates ... -
Tolvaptan in Later-Stage Autosomal Dominant Polycystic Kidney Disease.
(Massachusetts Medical Society, 2017-11-16)BACKGROUND: In a previous trial involving patients with early autosomal dominant polycystic kidney disease (ADPKD; estimated creatinine clearance, ≥60 ml per minute), the vasopressin V2-receptor antagonist tolvaptan slowed ... -
Transforming growth factor-β1 functional polymorphisms in myeloablative sibling hematopoietic stem cell transplantation
(Springer Nature [academic journals on nature.com], 2017-05-01)Hematopoietic stem cell transplantation (HSCT) with sibling donors (s.d.) is a life-saving intervention for patients with hematological malignancies. Numerous genetic factors have a role in transplant outcome. Several ... -
Treatment of Fabry's Disease with the Pharmacologic Chaperone Migalastat.
(Massachusetts Medical Society, 2016-08-11)BACKGROUND: Fabry's disease, an X-linked disorder of lysosomal α-galactosidase deficiency, leads to substrate accumulation in multiple organs. Migalastat, an oral pharmacologic chaperone, stabilizes specific mutant forms ...