Browsing Investigación Aplicada by Issue Date
Now showing items 121-140 of 225
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Multicenter Study of the Psychometric Properties of the New Demoralization Scale (DS-II) in Spanish-Speaking Advanced Cancer Patients.
(Elsevier, 2019-03-01)Abstract Context Demoralization is a state of existential distress in patients with advanced illness, typically with coping difficulties, feelings of loss of sense, and purpose in life and despair, among other things. ... -
Surveillance for Hepatocellular Carcinoma: Does the Place Where Ultrasound Is Performed Impact Its Effectiveness?
(Springer Science+Business Media, LLC, part of Springer Nature, 2019-03-01)Abstract Background: Biannual ultrasound (US) is recommended as the clinical screening tool for hepatocellular carcinoma (HCC). The effectiveness of surveillance according to the place where US is performed has not been ... -
A different gut microbiome linked to inflammation found in cirrhotic patients with and without hepatocellular carcinoma.
(Elsevier B.V. ScienceDirect, 2019-04-15)Abstract Introduction and aim: A pro-oncogenic intestinal microbiome was observed in murine models; however, no specific microbiome in patients with hepatocellular carcinoma (HCC) has been reported. We aimed to compare ... -
A different gut microbiome linked to inflammation found in cirrhotic patients with and without hepatocellular carcinoma
(Elsevier, 2019-04-15)Abstract Introduction and aim: A pro-oncogenic intestinal microbiome was observed in murine models; however, no specific microbiome in patients with hepatocellular carcinoma (HCC) has been reported. We aimed to compare ... -
Hypotonic and isotonic intravenous maintenance fluids in hospitalized controlled trial.
(BMJ Publishing Group, 2019-05-09)Abstract Objective: To compare the changes in serum sodium and acid/base status in patients receiving hypotonic and isotonic solutions. Design: A randomised, controlled and double-blind clinical trial. Setting: ... -
A Comprensive study of epigenetic alterations in hepatocellular carcicoma identifies potencial therapeutic targets.
(Elsevier B.V. All rights reserved, 2019-07-01)Abstract Background & aims: A causal link has recently been established between epigenetic alterations and hepatocarcinogenesis, indicating that epigenetic inhibition may have therapeutic potential. We aimed to identify ... -
Home-Based Care for Patients with Lysosomal Storage Disease: Experiences in Argentina
(Latin American Society Inborn Errors and Neonatal Screening, 2019-07-01)ABSTRACT Enzyme replacement therapy (ERT) is a long term treatment for patients who suffer from lysosomal storage disease. A transversal descriptive study was conducted to evaluate advantages and disadvantages of a ... -
Sarcoidosis al descubierto: Lo que deberíamos informar en las imágenes torácicas.
(Sociedad Argentina de Radiología, 2019-07-25)La sarcoidosis es una enfermedad granulomatosa no caseificante, multisistémica, de causa desconocida, que compromete al pulmón y a los ganglios linfáticos mediastinales entre el 90 y el 95% de los casos. También puede ... -
Children admitted to PICU after hematopoietic stem cell transplantation: A predictive model of mortality.
(Torres et al., 2019-08-16)Abstract Introduction: Hematopoietic stem cell transplantation (HSCT) in children is associated with severe complications that need admission to critical care units. Mortality in this group of patients remains high with ... -
Maritornes y la genética
(Archivos Argentinos de Pediatría, 2020)Maritornes es una de las figuras femeninas creadas por Cervantes en El Quijote. Aparece en varios capítulos de la primera parte, y es más importante su protagonismo en los capítulosXVI y XLIII. En la primera aparición ... -
Argentinian clinical genomics in a leukodystrophies and genetic leukoencephalopathies cohort: Diagnostic yield in our first 9 years
(Wiley, 2020-01)Abstract Introduction and objectives: Leukodystrophies and genetic leukoencephalopathies constitute a vast group of pathologies of the cerebral white matter. The large number of etiopathogenic genes and the frequent ... -
Allogeneic stem cell transplantation improves survival in relapsed Hodgkin lymphoma patients achieving complete remission after salvage treatment
(Springer Nature, 2020-01)Abstract Allogeneic stem cell transplant (alloSCT) is a current treatment option for patients with refractory/relapsed classic Hodgkin lymphoma (CHL), including those who have failed an autologous transplantation. We ... -
Glucocorticoid and progesterone mechanisms in photoreceptor survival
(Elsevier B.V. ScienceDirect, 2020-01-01)Abstract Death of retinal photoreceptors is the basis of prevalent blinding diseases. Since steroids might have a therapeutic role in retinal degenerations, we compared the protective effects of dexamethasone and progesterone ... -
Haploidentical transplant in adult patients with acute lymphoblastic leukemia in Argentina: a comparison with matched related and unrelated donors.
(Springer Nature, 2020-02)Abstract We aimed at analyzing the outcome of allogeneic stem cell transplant (ASCT) in adult patients with acute lymphoblastic leukemia (ALL), comparing Haploidentical (Haplo) with HLA-matched (sibling and unrelated) ... -
Increased androgen receptor expression in estrogen receptor-positive/progesterone receptor-negative breast cancer
(Springer, 2020-02)Abstract Purpose: Expression of estrogen receptor alpha (ER) and/or progesterone receptor (PR) defines luminal breast cancer. Even though androgen (AR) and glucocorticoid receptors (GR) are highly expressed in luminal ... -
Elucidating the mechanism of action of alpha-1-antitrypsin using retinal pigment epithelium cells exposed to high glucose. Potential use in diabetic retinopathy
(Potilinski et a, 2020-02-07)Abstract Background: Alpha-1-antitrypsin is a protein involved in avoidance of different processes that are seen in diabetic retinopathy pathogenesis. These processes include apoptosis, extracellular matrix remodeling and ... -
Recurrent dislocation of peroneal tendons. Minimally invasive technique for the deepening of the groove
(Medigraphic, 2020-03)Abstract in English, Spanish Introduction: Since William Clancy (1979) and Richard Ferkel (1997) publications, the technique of peroneal groove deepening in patients with chronic dislocation, has been used with very ... -
Surgical technique for approaching chronic or persistent macular holes: Two case reports
(Elsevier, 2020-04)Abstract Purpose: To report the anatomic and functional outcomes of an innovative surgical technique for either chronic or persistent macular holes (MHs). Observations: A consecutive retrospective interventional case ... -
Ilex paraguariensis extracts and its polyphenols prevent oxidative damage and senescence of human retinal pigment epithelium cells
(Elsevier Ltd. All rights reserved, 2020-04-01)Abstract Aged-related macular degeneration (AMD), a prevalent chronic disease leading to blindness, is associated with oxidative damage of the retinal pigment epithelium (RPE). Ilex paraguariensis (yerba mate, YM), widely ... -
Spanish multicenter real - life registry of retrievable vena cava filters (REFiVeC)
(SpringerOpen [Commercial Publisher], 2020-05)Abstract Background: The treatment of venous thromboembolic disease the treatment of choice is systemic anticoagulation. However, the interruption of the inferior vena cava with filters has been recommended when anticoagulation ...