Browsing Investigación básica. by Issue Date
Now showing items 1-20 of 79
-
Limitation of life-sustaining treatment in NICU: Physicians' beliefs and attitudes in the Buenos Aires region
(Elsevier, 2020-03)Abstract Objective: To explore the ethical beliefs and attitudes of Argentinean neonatologists regarding limitation of life-sustaining treatment (LST) for very sick infants. Methods: We used an anonymous questionnaire ... -
Immunotherapy for Hepatocellular Carcinoma: Is Latin America Ready for Primetime?
(AASLD, 2020-09)Potential conflict of interest: Nothing to report. Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer‐related death worldwide, and its mortality is increasing steadily.1 HCC incidence has grown in the ... -
Transcript Expression of Vesicular Glutamate Transporters in Rat Dorsal Root Ganglion and Spinal Cord Neurons: Impact of Spinal Blockade during Hindpaw Inflammation
(American Chemical Society, 2020-09)Abstract Studies in mouse, and to a lesser extent in rat, have revealed the neuroanatomical distribution of vesicular glutamate transporters (VGLUTs) and begun exposing the critical role of VGLUT2 and VGLUT3 in pain ... -
Significance of Simple Steatosis: An Update on the Clinical and Molecular Evidence
(MDPI [Commercial Publisher], 2020-11)Abstract Non-alcoholic fatty liver disease (NAFLD) is defined clinicopathologically by the accumulation of lipids in >5% of hepatocytes and the exclusion of secondary causes of fat accumulation. NAFLD encompasses a wide ... -
Resveratrol exerts anti-oxidant and anti-inflammatory actions and prevents oxaliplatin-induced mechanical and thermal allodynia
(Elsevier, 2020-12)Abstract Chemotherapy-induced peripheral neuropathic pain (CIPNP) is a frequent and devastating side effect of cancer therapy. No preventive strategies are currently available. We investigated the use of resveratrol (RESV) ... -
The odyssey of complex neurogenetic disorders: From undetermined to positive.
(Wiley, 2020-12)Abstract The genetic and phenotypic heterogeneity of neurogenetic diseases forces patients and their families into a "diagnostic odyssey." An increase in the variability of genetic disorders and the corresponding gene-disease ... -
A strategy to reduce medication prescription error in hospitalized patients
(Medicina Buenos Aires, 2021)Abstract in English, Spanish Prescription errors represent a relevant health problem. This work aims to analyze the medication prescription error in hospitalized patients before and after a multiple intervention. This is ... -
A functional platform to monitor SARS-CoV-2-specific T cell responses in vaccinated individuals and COVID-19 recovered patients
(Medicina Buenos Aires, 2021)Abstract in English, Spanish The rapid spread of the SARS-CoV-2, the causative agent of the emergent pandemic disease COVID-19, requires the urgent commitment of the immunology community to understand the adaptive immune ... -
Controversies during the COVID-19 pandemic
(Fundación Revista Medicina, 2021)Abstract in English, Spanish The COVID-19 pandemic has had an impact on public health and the global economy. The objective of this document was to update, according to the available evidence, the management of some basic ... -
Functional and druggability analysis of the SARS-CoV-2 proteome
(Elsevier, 2021-01)Abstract The infectious coronavirus disease (COVID-19) pandemic, caused by the coronavirus SARS-CoV-2, appeared in December 2019 in Wuhan, China, and has spread worldwide. As of today, more than 46 million people have ... -
Attitudes of Argentinean Neonatologists toward Resuscitation of Infants with Trisomies 21, 18, and 13: A Multicenter Survey
(Thieme Gruppe, 2021-01)Abstract Objective: This study was aimed to explore the attitude of Argentinean neonatologists in the delivery room on resuscitating infants with trisomies. Study design: An anonymous questionnaire was completed by ... -
Bronchogenic cyst in an unusual location
(SAGE Publications, 2021-01)Abstract Bronchogenic cysts are congenital anomalies of the respiratory tract, which can affect children or adults. In adults, these cysts may be asymptomatic or present with symptoms, most often pain or cough. Intrapericardial ... -
Complications in posterior ankle arthroscopy by classic and non-distraction portals
(Medigraphic, 2021-01)Abstract in English, Spanish Introducción: La artroscopía posterior de tobillo permite el diagnóstico y tratamiento de múltiples patologías a través de un mínimo trauma. Los portales posteriores, asociados o no a distracción ... -
A Year of Living Dangerously: Challenges and Recommendations for Safely Performing Ophthalmic Surgery During the COVID-19 Pandemic, from Start to Finish
(Taylor and Francis Group [Commercial Publisher] Dove Press [Imprint], 2021-01-15)Abstract The COVID-19 pandemic has forced all nations to take an active role in infection control incorporating recommendations and measures to control viral dissemination. The epidemiological impact is very diverse and ... -
[Idursulfase desensitization in a child with Hunter syndrome (mucopolysaccharidosis II)]
(sociedad argentina de pediatria, 2021-02)Abstract in English, Spanish Enzyme replacement therapy with idursulfase decreases morbidity and improves quality of life of patients with mucopolysaccharidosis ii. Immediate hypersensitivity reactions to this drug have ... -
Treatment of individual predictors with neural network algorithms improves Global Registry of Acute Coronary Events score discrimination
(Permanyer, 2021-02)Abstract in English, Spanish Objective: The aim of this study was to develop, train, and test different neural network (NN) algorithm-based models to improve the Global Registry of Acute Coronary Events (GRACE) score ... -
Artificial intelligence in the early stages of drug discovery
(Elsevier, 2021-02)Abstract Although the use of computational methods within the pharmaceutical industry is well established, there is an urgent need for new approaches that can improve and optimize the pipeline of drug discovery and ... -
Hepatokines and adipokines in NASH-related hepatocellular carcinoma
(Elsevier, 2021-02)Abstract The incidence of hepatocellular carcinoma (HCC) is increasing in industrialised societies; this is likely secondary to the increasing burden of non-alcoholic fatty liver disease (NAFLD), its progressive form ... -
Feeding difficulties in children and adolescents with spinal muscular atrophy type 2
(Elsevier, 2021-02)Abstract Disease course of feeding difficulties in spinal muscular atrophy type 2 is not well documented. Disease-modifying therapies rapidly change the trajectory of motor function and survival in spinal muscular atrophy, ... -
A Randomized Trial of Convalescent Plasma in Covid-19 Severe Pneumonia
(Massachusetts Medical Society [Society Publisher], 2021-02-01)Abstract Background: Convalescent plasma is frequently administered to patients with Covid-19 and has been reported, largely on the basis of observational data, to improve clinical outcomes. Minimal data are available ...