Browsing Investigación básica. by Issue Date
Now showing items 1-20 of 35
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A strategy to reduce medication prescription error in hospitalized patients
(Medicina Buenos Aires, 2021)Abstract in English, Spanish Prescription errors represent a relevant health problem. This work aims to analyze the medication prescription error in hospitalized patients before and after a multiple intervention. This is ... -
Attitudes of Argentinean Neonatologists toward Resuscitation of Infants with Trisomies 21, 18, and 13: A Multicenter Survey
(Thieme Gruppe, 2021-01)Abstract Objective: This study was aimed to explore the attitude of Argentinean neonatologists in the delivery room on resuscitating infants with trisomies. Study design: An anonymous questionnaire was completed by ... -
Bronchogenic cyst in an unusual location
(SAGE Publications, 2021-01)Abstract Bronchogenic cysts are congenital anomalies of the respiratory tract, which can affect children or adults. In adults, these cysts may be asymptomatic or present with symptoms, most often pain or cough. Intrapericardial ... -
A Year of Living Dangerously: Challenges and Recommendations for Safely Performing Ophthalmic Surgery During the COVID-19 Pandemic, from Start to Finish
(Taylor and Francis Group [Commercial Publisher] Dove Press [Imprint], 2021-01-15)Abstract The COVID-19 pandemic has forced all nations to take an active role in infection control incorporating recommendations and measures to control viral dissemination. The epidemiological impact is very diverse and ... -
Artificial intelligence in the early stages of drug discovery
(Elsevier, 2021-02)Abstract Although the use of computational methods within the pharmaceutical industry is well established, there is an urgent need for new approaches that can improve and optimize the pipeline of drug discovery and ... -
A Randomized Trial of Convalescent Plasma in Covid-19 Severe Pneumonia
(Massachusetts Medical Society [Society Publisher], 2021-02-01)Abstract Background: Convalescent plasma is frequently administered to patients with Covid-19 and has been reported, largely on the basis of observational data, to improve clinical outcomes. Minimal data are available ... -
4-methylumbelliferone-mediated polarization of M1 macrophages correlate with decreased hepatocellular carcinoma aggressiveness in mice
(Nature Research, 2021-03-01)Hepatocellular carcinoma (HCC) arises in the setting of advanced liver fibrosis, a dynamic and complex inflammatory disease. The tumor microenvironment (TME) is a mixture of cellular components including cancer cells, ... -
Budget impact analysis of using procalcitonin to optimize antimicrobial treatment for patients with suspected sepsis in the intensive care unit and hospitalized lower respiratory tract infections in Argentina
(Public Library of Science, 2021-04)Abstract Background: Inappropriate antibiotic use represents a major global threat. Sepsis and bacterial lower respiratory tract infections (LRTIs) have been linked to antimicrobial resistance, carrying important consequences ... -
Clinical characteristics and evolution of hematological patients and COVID-19 in Argentina: a report from the Argentine Society of Hematology
(Medicina Buenos Aires, 2021-05)Abstract in English, Spanish Individuals with malignancies and COVID-19 have a lower survival compared with the general population. However, the information about the impact of COVID-19 on the whole hematological population ... -
Acceleration of TAA-Induced Liver Fibrosis by Stress Exposure Is Associated with Upregulation of Nerve Growth Factor and Glycopattern Deviations
(MDPI [Commercial Publisher], 2021-05-01)Abstract Liver fibrosis results from many chronic injuries and may often progress to cirrhosis and hepatocellular carcinoma (HCC). In fact, up to 90% of HCC arise in a cirrhotic liver. Conversely, stress is implicated in ... -
Assessing the impact of COVID-19 on liver cancer management (CERO-19)
(Elsevier, 2021-06)Abstract Background & aims: The coronavirus disease 2019 (COVID-19) pandemic has posed unprecedented challenges to healthcare systems and it may have heavily impacted patients with liver cancer (LC). Herein, we evaluated ... -
Breast milk production and emotional state in mothers of very low birth weight infants
(sociedad argentina de pediatria, 2021-06)Abstract in English, Spanish Introduction: There is little evidence regarding the influence of emotional variables on breastfeeding among mothers of very low birth weight infants (VLBWIs). The objective of this study was ... -
Alcohol consumption leads to loss of healthy life, but the ADH1B*2 allele may still protect from NASH
(AME Publishing [Commercial Publisher], 2021-06-01)La enfermedad del hígado graso no alcohólico (NAFLD, por sus siglas en inglés) es ahora la causa más común de enfermedad hepática crónica en todo el mundo, afecta a casi una cuarta parte de la población mundial ( 1 , 2 ) ... -
Acute peritoneal dialysis, complications and outcomes in 389 children with STEC-HUS: a multicenter experience
(Springer [Commercial Publisher], 2021-06-01)Abstract Background: Management of acute kidney injury (AKI) in children with hemolytic uremic syndrome induced by a Shiga toxin-producing Escherichia coli infection (STEC-HUS) is supportive; however, 40 to 60% of cases ... -
An Ethical Pathway to Quality of Life in Critically Ill Newborns
(Taylor and Francis Group [Commercial Publisher] Routledge [Imprint], 2021-06-01)Abstract Advances in perinatology have permitted the survival of fragile neonates. Quality of life (QoL) has been considered a key element in medical decision-making. In this review we analyse the role of QoL regarding ... -
A few challenges in mucopolysaccharidosis type I
(2021-06-01)RESUMEN Se describen como desafíos actuales en mucopolisacaridosis I la necesidad de una clasificación adecuada, vinculándola a las indicaciones terapéuticas; el diagnóstico temprano desde la pesquisa neonatal, ... -
An inflammatory aging clock (iAge) based on deep learning tracks multimorbidity, immunosenescence, frailty and cardiovascular aging
(Nature Research [Commercial Publisher], 2021-07)Abstract While many diseases of aging have been linked to the immunological system, immune metrics capable of identifying the most at-risk individuals are lacking. From the blood immunome of 1,001 individuals aged 8–96 ... -
Bioinformatic analysis of RHO family of GTPases identifies RAC1 pharmacological inhibition as a new therapeutic strategy for hepatocellular carcinoma
(BMJ Publishing Group, 2021-07)Abstract Objective: The RHO family of GTPases, particularly RAC1, has been linked with hepatocarcinogenesis, suggesting that their inhibition might be a rational therapeutic approach. We aimed to identify and target ... -
An Update on Hepatocellular Carcinoma in Chronic Kidney Disease
(MDPI [Commercial Publisher], 2021-07)Abstract Chronic kidney disease is a major public health issue globally and the risk of cancer (including HCC) is greater in patients on long-term dialysis and kidney transplant compared with the general population. ... -
Argentine Consensus of the Diagnosis and Treatment of Hereditary Angioedema
(Revista alergia mexico, 2021-07)Abstract in English, Spanish Objectives: Hereditary angioedema (HAE) is a rare disease. During the last years, many studies and advances have been developed with the aim of better understanding the pathophysiology, as ...