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An inflammatory aging clock (iAge) based on deep learning tracks multimorbidity, immunosenescence, frailty and cardiovascular aging
(Nature Research [Commercial Publisher], 2021-07)
Abstract
While many diseases of aging have been linked to the immunological system, immune metrics
capable of identifying the most at-risk individuals are lacking. From the blood immunome of
1,001 individuals aged 8–96 ...
Feeding difficulties in children and adolescents with spinal muscular atrophy type 2
(Elsevier, 2021-02)
Abstract
Disease course of feeding difficulties in spinal muscular atrophy type 2 is not well documented. Disease-modifying therapies rapidly change the trajectory of motor function and survival in spinal muscular atrophy, ...
Alcohol consumption leads to loss of healthy life, but the ADH1B*2 allele may still protect from NASH
(AME Publishing [Commercial Publisher], 2021-06-01)
La enfermedad del hígado graso no alcohólico (NAFLD, por sus siglas en inglés) es ahora la causa más común de enfermedad hepática crónica en todo el mundo, afecta a casi una cuarta parte de la población mundial ( 1 , 2 ) ...
A functional platform to monitor SARS-CoV-2-specific T cell responses in vaccinated individuals and COVID-19 recovered patients
(Medicina Buenos Aires, 2021)
Abstract in English, Spanish
The rapid spread of the SARS-CoV-2, the causative agent of the emergent pandemic disease COVID-19, requires the urgent commitment of the immunology community to understand the adaptive immune ...
Bronchogenic cyst in an unusual location
(SAGE Publications, 2021-01)
Abstract
Bronchogenic cysts are congenital anomalies of the respiratory tract, which can affect children or adults. In adults, these cysts may be asymptomatic or present with symptoms, most often pain or cough. Intrapericardial ...
Optical clearing reveals TNBS-induced morphological changes of VGLUT2-positive nerve fibers in mouse colorectum
(American Physiological Society, 2021-04)
Abstract
Colorectal hypersensitivity and sensitization of both mechanosensitive and mechanically insensitive afferents develop after intracolonic instillation of 2,4,6-trinitrobenzenesulfonic acid (TNBS) in the mouse, a ...
Acute peritoneal dialysis, complications and outcomes in 389 children with STEC-HUS: a multicenter experience
(Springer [Commercial Publisher], 2021-06-01)
Abstract
Background: Management of acute kidney injury (AKI) in children with hemolytic uremic syndrome induced by a Shiga toxin-producing Escherichia coli infection (STEC-HUS) is supportive; however, 40 to 60% of cases ...
A Machine Learning Model to Predict Drug Transfer Across the Human Placenta Barrier
(Frontiers Media, 2021-07-01)
Abstract
The development of computational models for assessing the transfer of chemicals across the placental membrane would be of the utmost importance in drug discovery campaigns, in order to develop safe therapeutic ...
Bilateral central retinal artery occlusion: An exceptional complication after frontal parasagittal meningioma resection
(Scientific Scholar, 2021-08)
Abstract
Background: Central retinal artery occlusion (CRAO) is a rare acute disease associated with great morbidity. It is reported as a complication of surgical procedures, but rarely associated with brain surgery and ...
COVID-19: Consequences for Children With Cancer in Turkey and Globally
(Turkish pediatric association, 2021-07)
INTRODUCTION
The current outbreak of COVID-19 that was first reported from Wuhan, China, on December
31, 2019 was declared a pandemic on March 11, 2020 by the World Health Organization
(WHO).1
The first case in Turkey ...