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Up-regulation of pro-angiogenic molecules and events does not relate with an angiogenic switch in metastatic osteosarcoma cells but to cell survival features
(Springer, 2021-08)
Abstract
Osteosarcoma (OS) is the most frequent malignant bone tumor, affecting predominantly children. Metastases represent a major clinical challenge and an estimated 80% would present undetectable micrometastases at ...
Evaluation of Silicone Fluids and Resins as CO2 Thickeners for Enhanced Oil Recovery Using a Computational and Experimental Approach
(American Chemical Society [Society Publisher], 2021-09)
Abstract
CO2 thickeners have the potential to be a game changer for enhanced oil recovery, carbon capture utilization and storage, and hydraulic fracturing. Thickener design is challenging due to polymers' low solubility ...
New insights into oxidative stress and immune mechanisms involved in age-related macular degeneration tackled by novel therapies
(Elsevier, 2021-05)
Abstract
The prevalence of age-related macular degeneration (AMD) has increased in the last years. Although anti-VEGF agents have improved the prognosis of exudative AMD, dry AMD has still devastating effects on elderly ...
An Ethical Pathway to Quality of Life in Critically Ill Newborns
(Taylor and Francis Group [Commercial Publisher] Routledge [Imprint], 2021-06-01)
Abstract
Advances in perinatology have permitted the survival of fragile neonates. Quality of life (QoL) has been considered a key element in medical decision-making. In this review we analyse the role of QoL regarding ...
Alternative Technique for Sphenopalatine Ganglion Electrode Fixation: Avoiding Lead Migration
(Wiley [Commercial Publisher], 2021-12)
La estimulación del ganglio esfenopalatino (SPG) se propuso por primera vez en 2007 ( 1. ). Existe una fuerte evidencia que sugiere que la estimulación SPG es efectiva en el tratamiento de la cefalea en brotes (Grado de ...
Consensus on Treatment and Follow-Up for Biochemical Recurrence in Castration-Sensitive Prostate Cancer: A Report From the First Global Prostate Cancer Consensus Conference for Developing Countries
(American Society of Clinical Oncology, 2021-04)
Abstract
Purpose: To present a summary of the treatment and follow-up recommendations for the biochemical recurrence in castration-sensitive prostate cancer (PCa) acquired through a questionnaire administered to 99 PCa ...
Current Status of Training and Certification for Congenital Heart Surgery Around the World: Proceedings of the Meetings of the Global Council on Education for Congenital Heart Surgery of the World Society for Pediatric and Congenital Heart Surgery
(SAGE Publications, 2021-05)
Abstract
The optimal training of the highly specialized congenital heart surgeon is a long and complex process, which is a significant challenge in most parts of the world. The World Society for Pediatric and Congenital ...
An Update on Hepatocellular Carcinoma in Chronic Kidney Disease
(MDPI [Commercial Publisher], 2021-07)
Abstract
Chronic kidney disease is a major public health issue globally and the risk of cancer (including HCC) is greater in patients on long-term dialysis and kidney transplant compared with the general population. ...
Development of an Improved Guanidine-Based Rac1 Inhibitor with in vivo Activity against Non-Small Cell Lung Cancer
(Wiley, 2021-03)
Abstract
The Rho GTPase Rac1 is involved in the control of cytoskeleton reorganization and other fundamental cellular functions. Aberrant activity of Rac1 and its regulators is common in human cancer. In particular, ...
Clinical presentation and outcomes of the first patients with COVID-19 in Argentina: Results of 207079 cases from a national database
(Public Library of Science, 2021-02)
Abstract
Background: There is limited evidence on the clinical characteristics of SARS-CoV-2 infection in Latin America. We present findings from a nationwide study in Argentina.
Research question: What is disease ...