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Combination of pose and rank consensus in docking-based virtual screening: the best of both worlds
(Royal Society of Chemistry, 2021-11)
Abstract
The use of high-throughput docking (HTD) in the drug discovery pipeline is today widely established. In spite of methodological improvements in docking accuracy (pose prediction), scoring power, ranking power, ...
Corynebacterium kroppenstedtii breast infections: Report of four cases
(Elsevier, 2021-10)
Abstract
Corynebacterium kroppenstedtii is an immobile, non-sporulated, glucose-fermenting and lipophilic gram-positive rod of the skin microbiota. In recent years, numerous isolates of this species have been reported ...
Increased risk of preneoplastic colonic lesions and colorectal carcinoma in acromegaly: multicenter case-control study
(Springer, 2021-02)
Abstract
Purpose: Current international guidelines recommend colonoscopy in patients with acromegaly at the time of diagnosis, even though the risk of developing colorectal neoplasm is still controversial. The main objective ...
Reply
(Elsevier, 2021-03)
Hepatokines and adipokines in NASH-related hepatocellular carcinoma
(Elsevier, 2021-02)
Abstract
The incidence of hepatocellular carcinoma (HCC) is increasing in industrialised societies; this is likely secondary to the increasing burden of non-alcoholic fatty liver disease (NAFLD), its progressive form ...
[Propranolol treatment in Kasabach-Merritt Syndrome secondary to congenital hepatic hemangioma. Clinical case]
(Archivos Argentinos de Pediatría, 2021-02)
Abstract in English, Spanish
Hepatic hemangioma is the most common benign liver tumor. It can be congenital or infantile with different outcomes and complications. The clinical manifestation varies from asymptomatic to ...
Acceleration of TAA-Induced Liver Fibrosis by Stress Exposure Is Associated with Upregulation of Nerve Growth Factor and Glycopattern Deviations
(MDPI [Commercial Publisher], 2021-05-01)
Abstract
Liver fibrosis results from many chronic injuries and may often progress to cirrhosis and hepatocellular carcinoma (HCC). In fact, up to 90% of HCC arise in a cirrhotic liver. Conversely, stress is implicated in ...
The Latin American Association for the Study of the Liver (ALEH) position statement on the redefinition of fatty liver disease
(Elsevier, 2021-01)
Abstract
The Latin American Association for the Study of the Liver (Asociación Latinoamericana para el Estudio del Hígado; ALEH) represents liver professionals in Latin America with the mission of promoting liver health ...
Cross-Cultural Adaptation and Psychometric Evaluation of a Second Victim Experience and Support Tool (SVEST)
(Lippincott, Williams & Wilkins, 2021-12)
Abstract
Introduction
The second victim is defined as the health professionals who commit an error and are traumatized by the event manifesting psychological, cognitive, and/or physical reactions that have a personal ...
Is perineal hypermobility an independent predictor of obstructive defecation?
(Springer, 2021-09)
Abstract
Introduction and hypothesis: Symptoms of obstructed defecation (OD) and anatomical abnormalities of the posterior compartment are prevalent in urogynecological patients. The aim of this study was to determine ...