| dc.description.abstract | Reduction of inappropriate prescriptions and adverse effects to medications in hospitalized
elderly patients. Together, potentially inappropriate prescribing of medications (PIP) and appropriate prescribing omission (APO) constitute a problem that requires multiple interventions to reduce its size and
the occurrence of adverse drug events (ADE). This study aims to assess PIP, APO, ADE before and after the
intervention of a clinical pharmacist over medical prescriptions for elderly hospitalized patients. In a beforeafter study, a total of 16 542 prescriptions for 1262 patients were analyzed applying the criteria defined in both
STOPP- START (screening tool of older people’s prescriptions and screening tool to alert to right treatment). The
intervention consisted in lectures and publications on STOPP-START criteria made available to all the areas of the
hospital and suggestions made by the clinical pharmacist to the physician on each individual prescription. Before
intervention, PIM was 48.9% on admission and 46.1% at discharge, while after the intervention it was 47.4% on
admission and 16.7% at discharge. APO was 10% on admission and 7.6% at discharge, while after intervention
it was 12.2% on admission and 7.9% at discharge. ADE were 50.9% before and 34.4% after intervention. The
frequency of return to emergency was 12.2% and 4.7% before and after intervention. PIM, EAM, conciliation
error, clinically serious drug interaction, and delirium were reduced to statistically significant levels. In line with
various international studies, the intervention showed to attain positive results. | en_US |
