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dc.contributor.authorCoronel, María F.
dc.contributor.authorLabombarda, Florencia.
dc.contributor.authorGonzález, Susana.
dc.date.accessioned2019-11-05T21:41:46Z
dc.date.available2019-11-05T21:41:46Z
dc.date.issued2016-04-11
dc.identifier.citationSteroids. 2016 Jun;110:77-87.en_US
dc.identifier.issn0039-128X
dc.identifier.urihttps://riu.austral.edu.ar/handle/123456789/749
dc.description.abstractThe present review discusses the potential role of neurosteroids / neuroactive steroids in the regulation of nociceptive and neuropathic pain, and recapitulates the current knowledge on the main mechanisms involved in the reduction of pain, especially those occurring at the dorsal horn of the spinal cord, a crucial site for nociceptive processing. We will make special focus on progesterone and its derivative allopregnanolone, which have been shown to exert remarkable actions in order to prevent or reverse the maladaptive changes and pain behaviors that arise after nervous system damage in various experimental neuropathic conditions.en_US
dc.language.isoenen_US
dc.publisherElsevier Inc. All rights reserved.en_US
dc.subjectAllopregnanoloneen_US
dc.subjectChronic painen_US
dc.subjectNeurosteroidsen_US
dc.subjectNociceptive painen_US
dc.subjectProgesteroneen_US
dc.subjectSpinal cord dorsal hornen_US
dc.titleNeuroactive steroids, nociception and neuropathic pain: A flashback to go forward.en_US
dc.typeArticleen_US


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