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Hepatotoxicity Induced by Coxibs: How Concerned Should We Be?
(Taylor & Francis, 2016-08-26)
Introduction: The selective inhibitors of COX-2, coxibs, are nonsteroidal anti-inflammatory drugs (NSAIDs) that have much better gastrointestinal safety profile as compared with non-selective NSAIDs. In this review, we ...
The Latin American DILI Registry Experience: A Successful Ongoing Collaborative Strategic Initiative.
(MDPI, 2016-02-25)
Drug induced liver injury (DILI) is a rare but well recognized serious adverse reaction. Pre-marketing studies may not detect liver injury, and DILI becomes very often apparent after the drug is launched to the market. ...
Drug-induced liver injury: A management position paper from the Latin American Association for Study of the liver
(Elsevier, 2021-09)
Abstract
Idiosyncratic drug-induced liver injury (DILI) caused by xenobiotics (drugs, herbals and dietary supplements) is an uncommon cause of liver disease presenting with a wide range of phenotypes and disease severity, ...
Serious liver injury induced by Nimesulide: an international collaborative study
(Springer, 2021-04)
Abstract
Nimesulide is a non-steroidal anti-inflammatory drug still marketed in many countries. We aim to analyze the clinical phenotype, outcome, and histological features of nimesulide-induced liver injury (nimesulide-DILI). ...