Browsing Investigación Aplicada by Author "Piñero, Federico."
Now showing items 1-20 of 33
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Adherence to Barcelona Clinic Liver Cancer therapeutic algorithm for hepatocellular carcinoma in the daily practice: a multicenter cohort study from Argentina
Piñero, Federico.; Marciano, Sebastián.; Fernández, Nora.; Silva, Jorge.; Zambelo, Yanina.; Cobos, Manuel.; Zerega, Alina.; et al. (Wolters Kluwer Health, Inc. All rights reserved, 2018-04-30)Abstract Background and aim Adherence to the Barcelona Clinic Liver Cancer (BCLC) staging algorithm for the treatment of hepatocellular carcinoma is challenging in the daily practice. We aimed to analyze adherence to ... -
Argentinian clinical practice guideline for surveillance, diagnosis, staging and treatment of hepatocellular carcinoma
Piñero, Federico.; Tisi Baña, Matías.; Ridruejo, Ezequiel.; Et al. (Elsevier, 2020-10)Abstract The A.A.E.E.H has developed this guideline for the best care of patients with hepatocellular carcinoma (HCC) from Argentina. It was done from May 2018 to March 2020. Specific clinical research questions were ... -
Biomarkers in Hepatocellular Carcinoma: Diagnosis, Prognosis and Treatment Response Assessment
Piñero, Federico.; Dirchwolf, Melisa.; Pessôa, Mário. (2020-06)Abstract Hepatocellular carcinoma (HCC) is one of the main cancer-related causes of death worldwide. Thus, there is a constant search for improvement in screening, diagnosis, and treatment strategies to improve the prognosis ... -
A different gut microbiome linked to inflammation found in cirrhotic patients with and without hepatocellular carcinoma
Piñero, Federico.; Vazquez, Martín.; Baré, Patricia.; Rohr, Cristian.; Mendizabal, Manuel.; Sciara, Mariela.; Alonsoa, Cristina. (Elsevier, 2019-04-15)Abstract Introduction and aim: A pro-oncogenic intestinal microbiome was observed in murine models; however, no specific microbiome in patients with hepatocellular carcinoma (HCC) has been reported. We aimed to compare ... -
A different gut microbiome linked to inflammation found in cirrhotic patients with and without hepatocellular carcinoma.
Piñero, Federico.; Vazquez, Martín.; Baré, Patricia.; Rohr, Cristian.; Mendizabal, Manuel.; Sciarac, Mariela.; Alonsoa, Cristina.; et al. (Elsevier B.V. ScienceDirect, 2019-04-15)Abstract Introduction and aim: A pro-oncogenic intestinal microbiome was observed in murine models; however, no specific microbiome in patients with hepatocellular carcinoma (HCC) has been reported. We aimed to compare ... -
Direct-acting antiviral treatment failure in genotype 2 hepatitis C chronic infection
Piñero, Federico.; Mendizabal, Manuel.; Silva, Marcelo.; Et al. (Wiley, 2021-02)Comment J Viral Hepat . 2021 Feb;28(2):446-447. doi: 10.1111/jvh.13433. Epub 2020 Nov 18. Direct-acting antiviral treatment failure in genotype 2 hepatitis C chronic infection Ezequiel Ridruejo 1 2 3, Federico Piñero 2 ... -
Disease Progression in Patients With Hepatitis C Virus Infection Treated With Direct-Acting Antiviral Agents.
Mendizabal, Manuel.; Piñero, Federico.; Ridruejo, Ezequiel.; Et al. (Elsevier, 2020-10)Abstract Background & aims: Little is known about how a sustained virologic response (SVR) to treatment of hepatitis C virus infection with direct-acting antivirals (DAAs) affects patient mortality and development of new ... -
Dropout rate from the liver transplant waiting list because of hepatocellular carcinoma progression in hepatitis C virus-infected patients treated with direct-acting antivirals.
Piñero, Federico.; Silva, Marcelo. (Wiley, 2017-10-01)We have read with interest the article recently pub-lished by Zanetto et al. inLiver Transplantationregarding the effect on radiologic progression of hepa-tocellular carcinoma (HCC) after the treatment withdirect-acting ... -
Fatty liver disease, an emerging etiology of hepatocellular carcinoma in Argentina
Piñero, Federico.; Pages, Josefina.; Marciano, Sebastián.; Fernández, Nora.; Silva, Jorge.; Anders, Margarita.; Zerega, Alina.; et al. (Baishideng Publishing Group Inc, 2018-01-27)Abstract Aim: To investigate any changing trends in the etiologies of hepatocellular carcinoma (HCC) in Argentina during the last years. Methods: A longitudinal cohort study was conducted by 14 regional hospitals ... -
Fatty liver disease, an emerging etiology of hepatocellular carcinoma in Argentina.
Piñero, Federico.; Pages, Josefina.; Marciano, Sebastián.; Fernandez, Nora.; Silva, Jorge.; Anders, Margarita.; Zerega, Alina.; et al. (Baishideng Publishing Group, 2018-01-27)AIM: To investigate any changing trends in the etiologies of hepatocellular carcinoma (HCC) in Argentina during the last years. METHODS: A longitudinal cohort study was conducted by 14 regional hospitals starting in ... -
Hepatocellular carcinoma in Latin America: Diagnosis and treatment challenges
Piñero, Federico.; Poniachk, Jaime.; Ridruejo, Ezequiel.; Silva, Marcelo. (Baishideng Publishing Group, 2018-10-07)Abstract Latin America, a region with a population greater than 600000000 individuals, is well known due to its wide geographic, socio-cultural and economic heterogeneity. Access to health care remains as the main barrier ... -
Identifying patients at higher risk of hepatocellular carcinoma recurrence after liver transplantation in a multicenter cohort study from Argentina.
Piñero, Federico.; Marciano, Sebastián.; Anders, Margarita.; et al. (Wolters Kluwer Health, Inc., 2016-04-28)BACKGROUND AND AIM: The Up-to-7 criteria on the basis of the explanted liver features categorize patients at higher risk of hepatocellular carcinoma (HCC) recurrence after liver transplantation (LT). The aim of this study ... -
Incidence, risk factors, and outcomes related with neurological events after liver transplantation in adult and pediatric recipients.
Piñero, Federico.; Cheang, Yu.; Mendizabal, Manuel.; Cagliani, Joaquin.; Gonzalez, Ariel.; Pages, Josefina.; Colaci, Carla.; et al. (Wiley, 2018-02-07)Controversy exists whether NE after LT are more frequently observed in children or adults. We aimed to compare the incidence and outcomes for NE after LT in pediatric and adult recipients. A single-center cohort study, ... -
Incidence, risk factors, and outcomes related with neurological events after liver transplantation in adult and pediatric recipients.
Piñero, Federico.; Cheang, Yu.; Mendizabal, Manuel.; Cagliani, Joaquín.; Gonzalez, Ariel.; Pages, Josefina.; Colaci, Carla.; et al. (John Wiley & Sons A/S. Published by John Wiley & Sons Ltd, 2018-02-07)Abstract Controversy exists whether NE after LT are more frequently observed in children or adults. We aimed to compare the incidence and outcomes for NE after LT in pediatric and adult recipients. A single-center cohort ... -
International study on the outcome of locoregional therapy for liver transplant in hepatocellular carcinoma beyond Milan criteria
Piñero, Federico.; Degroote, Helena.; Costentin, Charlotte.; Et al. (Elsevier, 2021-07)Abstract Background & aims: Good outcomes after liver transplantation (LT) have been reported after successfully downstaging to Milan criteria in more advanced hepatocellular carcinoma (HCC). We aimed to compare post-LT ... -
Isolated Intrapulmonary Vascular Dilatations and the Risk of Developing Hepatopulmonary Syndrome in Liver Transplant Candidates.
Mendizabal, Manuel.; Goldberg, DS.; Piñero, Federico.; Arufe, Diego.; De la Fuente, María J.; Testa, Pablo.; Coronel, Matias.; et al. (Elsevier, 2017-08-01)BACKGROUND: The natural history of intrapulmonary vascular dilations (IPVD) and their impact on patient outcomes in the setting of portal hypertension has only been described in small series. AIMS: To assess the ... -
The Latin American DILI Registry Experience: A Successful Ongoing Collaborative Strategic Initiative.
Bessone, Fernando.; Hernandez, Nelia.; Lucena, Isabel.; Andrade, Raul.; Piñero, Federico.; Mendizabal, Manuel. (MDPI, 2016-02-25)Drug induced liver injury (DILI) is a rare but well recognized serious adverse reaction. Pre-marketing studies may not detect liver injury, and DILI becomes very often apparent after the drug is launched to the market. ... -
LI-RADS 4 or 5 categorization may not be clinically relevant for decision-making processes: A prospective cohort study
Piñero, Federico.; Thompson, Marcos.; Diaz Telli, Federico.; Et al. (Elsevier, 2020-11)Abstract Introduction and objectives: The liver imaging reporting data system (LI-RADS) for hepatocellular carcinoma (HCC) was proposed to standardize and enhance consensus of reporting. However, clinical utility of LI-RADS ... -
Liver disease and dyslipidemia as a manifestation of lysosomal acid lipase deficiency (LAL-D). Clinical and diagnostic aspects, and a new treatment. An update.
Bay, Luisa.; Cañero Velasco, Cristina.; Ciocca, Mirta.; Cotti, Andrea.; Cuarterolo, Miriam.; Fainboim, Alejandro.; Piñero, Federico.; et al. (Sociedad Argentina de Pediatría., 2017-06-01)Lysosomal acid lipase deficiency (LAL-D) is still a little recognized genetic disease with significant morbidity and mortality in children and adults. This document provides guidance on when to suspect LAL-D and how to ... -
Liver transplantation for hepatocellular carcinoma: evaluation of the alpha-fetoprotein model in a multicenter cohort from Latin America.
Piñero, Federico.; Tisi Baña, Matias.; Ataide, Elaine C.; Hoyos Duque, Sergio.; Marciano, Sebastián.; Varón, Adriana.; Anders, Margarita.; et al. (Wiley, 2016-11-01)BACKGROUND & AIMS: The French alpha-fetoprotein (AFP) model has recently shown superior results compared to Milan criteria (MC) for prediction of hepatocellular carcinoma (HCC) recurrence after liver transplantation (LT) ...