Browsing Investigación Aplicada by Author "Brumovsky, Pablo."
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Dorsal root ganglion neurons and tyrosine hydroxylase--an intriguing association with implications for sensation and pain.
Brumovsky, Pablo. (International Association for the Study of Pain, 2016-02-01)Tyrosine hydroxylase (TH) is a rate-limiting enzyme broadly expressed in noradrenergic and dopaminergic neurons in the central nervous system [57,70]. TH is also expressed by peripheral sympathetic neurons [98] as well ... -
Spinal neuropeptide expression and neuropathic behavior in the acute and chronic phases after spinal cord injury: Effects of progesterone administration.
Coronel, María F.; Villar, Marcelo.; Brumovsky, Pablo.; Gonzalez, Susana. (Elsevier Inc. All rights reserved., 2017-02)Patients with spinal cord injury (SCI) develop chronic pain that severely compromises their quality of life. We have previously reported that progesterone (PG), a neuroprotective steroid, could offer a promising therapeutic ... -
Systemic Transplantation of Bone Marrow Mononuclear Cells Promotes Axonal Regeneration and Analgesia in a Model of Wallerian Degeneration
Usach, Vanina.; Malet, Mariana.; López, Margarita.; Lavalle, Lucia.; Piñero, Gonzalo.; Saccoliti, María.; Brumovsky, Pablo. (Lippincott, Williams & Wilkins, 2017-07)Background Reinnervation timing after nerve injury is critical for favorable axonal regeneration, remyelination, and clinical improvement. Considering bone marrow mononuclear cells (BMMC) are easily obtained and readily ...