Browsing Investigación Aplicada by Issue Date
Now showing items 81-100 of 225
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Uncovering the in vivo source of adult neural crest stem cells.
(Mary Ann Liebert, 2017-03-01)Some late embryonic and adult postmigratory neural crest-derived cells (NCDCs) from diverse tissues were shown to grow as multipotent neurospheres. Neural crest stem cells (NCSCs) contained in these spheres were found to ... -
Loss of dystrophin is associated with increased myocardial stiffness in a model of left ventricular hypertrophy.
(Springer, 2017-03-18)Transition from compensated to decompensated left ventricular hypertrophy (LVH) is accompanied by functional and structural changes. Here, the aim was to evaluate dystrophin expression in murine models and human subjects ... -
Loss of dystrophin is associated with increased myocardial stiffness in a model of left ventricular hypertrophy.
(Springer, 2017-03-18)Transition from compensated to decompensated left ventricular hypertrophy (LVH) is accompanied by functional and structural changes. Here, the aim was to evaluate dystrophin expression in murine models and human subjects ... -
Ombitasvir / paritaprevir / ritonavir / dasabuvir ± ribavirina es segura y efectiva en el HCV - infectados pacientes en una vida real cohorte de América Latina .
(Wiley, 2017-03-29)Information about the use of ombitasvir/paritaprevir/ritonavir/dasabuvir ± ribavirin (OBV/PTV/r/DSV ± RBV) in real-clinical practice in Latin America is scarce. We aimed to confirm safety and effectiveness of OBV/PTV/r/DSV ± RBV ... -
Response to "Comments on 'The Effects of Fat Harvesting and Preparation, Air Exposure, Obesity, and Stem Cell Enrichment on Adipocyte Viability Prior to Graft Transplantation'".
(Oxford University Press, 2017-04-01)Response to “Comments on ‘The Effects of Fat Harvesting and Preparation, Air Exposure, Obesity, and Stem Cell Enrichment on Adipocyte Viability Prior to Graft Transplantation’” -
Predictive models for recurrence risk of hepatocellular carcinoma after liver transplantation: Still an unmet need.
(Wiley, 2017-05-01)Recurrence of hepatocellular carcinoma (HCC) after liver transplanta-tion (LT) is a frightening issue. It is considered a systemic advanced stage with poor survival rate from the time of its diagnosis, with few therapeutic ... -
Latin America: the next region for haematopoietic transplant progress.
(Springer Nature [academic journals on nature.com], 2017-05-01)Haematopoietic cell transplant activity in the 28 countries comprising Latin America is poorly defined. We conducted a voluntary survey of members of the Latin American Bone Marrow Transplantation Group regarding transplant ... -
Transforming growth factor-β1 functional polymorphisms in myeloablative sibling hematopoietic stem cell transplantation
(Springer Nature [academic journals on nature.com], 2017-05-01)Hematopoietic stem cell transplantation (HSCT) with sibling donors (s.d.) is a life-saving intervention for patients with hematological malignancies. Numerous genetic factors have a role in transplant outcome. Several ... -
Liver disease and dyslipidemia as a manifestation of lysosomal acid lipase deficiency (LAL-D). Clinical and diagnostic aspects, and a new treatment. An update.
(Sociedad Argentina de Pediatría., 2017-06-01)Lysosomal acid lipase deficiency (LAL-D) is still a little recognized genetic disease with significant morbidity and mortality in children and adults. This document provides guidance on when to suspect LAL-D and how to ... -
En las fronteras de la ética de la investigación clínica: ajustando las normas al progreso.
(Revista Argentina de Cardiología, 2017-06-01)Es claro que las normas pueden ser buenas, regulares o malas. Dada la lógica normativa y burocrática, no hay mucho énfasis ni investigación sobre las malas normas en investigación clínica y su impacto en la producción ... -
Chronic hepatitis C and chronic kidney disease: Advances, limitations and unchartered territories.
(Wiley, 2017-06-01)Over the past few years, treatment options for chronic hepatitis C virus (HCV) infection have evolved dramatically. The current approved interferon-free direct-acting antiviral (DAA) regimens have been shown to be safe and ... -
Developing multicenter consortia in liver disease in Latin America: Challenges and opportunities.
(Wiley, 2017-06-07)The development of consortia has been useful for exploring challenging scenarios and uncharted territories in liver disease treatments. Several consortia already developed in the United States and Europe have become key ... -
Systemic Transplantation of Bone Marrow Mononuclear Cells Promotes Axonal Regeneration and Analgesia in a Model of Wallerian Degeneration
(Lippincott, Williams & Wilkins, 2017-07)Background Reinnervation timing after nerve injury is critical for favorable axonal regeneration, remyelination, and clinical improvement. Considering bone marrow mononuclear cells (BMMC) are easily obtained and readily ... -
Isolated Intrapulmonary Vascular Dilatations and the Risk of Developing Hepatopulmonary Syndrome in Liver Transplant Candidates.
(Elsevier, 2017-08-01)BACKGROUND: The natural history of intrapulmonary vascular dilations (IPVD) and their impact on patient outcomes in the setting of portal hypertension has only been described in small series. AIMS: To assess the ... -
Association Between Cigarette Smoking Prevalence and Income Level: A Systematic Review and Meta-Analysis.
(Oxford University Press, 2017-09)INTRODUCTION: Previous evidence linked low socioeconomic status with higher smoking prevalence. Our objective was to assess the strength of this association in the world population, updating a previous work. METHODS: ... -
Ombitasvir/paritaprevir/ritonavir/dasabuvir ± ribavirin is safe and effective in HCV-infected patients in a real-life cohort from Latin America.
(Wiley, 2017-09-01)Information about the use of ombitasvir/paritaprevir/ritonavir/dasabuvir ± ribavirin (OBV/PTV/r/DSV ± RBV) in real-clinical practice in Latin America is scarce. We aimed to confirm safety and effectiveness of OBV/PTV/r/DSV ± RBV ... -
Dropout rate from the liver transplant waiting list because of hepatocellular carcinoma progression in hepatitis C virus-infected patients treated with direct-acting antivirals.
(Wiley, 2017-10-01)We have read with interest the article recently pub-lished by Zanetto et al. inLiver Transplantationregarding the effect on radiologic progression of hepa-tocellular carcinoma (HCC) after the treatment withdirect-acting ... -
Hematopoietic Cell Transplantation-Specific Comorbidity Index Predicts Morbidity and Mortality in Autologous Stem Cell Transplantation.
(Elsevier, 2017-10-01)The hematopoietic cell transplantation-specific comorbidity index (HCT-CI) score is a useful tool to assess the risk for nonrelapse mortality (NRM) after allogeneic hematopoietic stem cell transplantation. Although the ... -
Vulvar Langerhans cell histiocytosis and thalidomide: an effective treatment option
(Wiley, 2017-10-25)Langerhans cell histiocytosis (LCH) is a disease characterized by clonal proliferation and a pathological infiltration of Langerhans cells in one or more organs, in which almost every tissue may be involved. Its incidence ... -
Hematopoietic Stem-Cell Gene Therapy for Cerebral Adrenoleukodystrophy.
(Massachusetts Medical Society, 2017-10-26)BACKGROUND: In X-linked adrenoleukodystrophy, mutations in ABCD1 lead to loss of function of the ALD protein. Cerebral adrenoleukodystrophy is characterized by demyelination and neurodegeneration. Disease progression, ...