Browsing Investigación Aplicada by Issue Date
Now showing items 201-220 of 225
-
Practice-Changing Use of the 21-Gene Test for the Management of Patients With Early-Stage Breast Cancer in Latin America
(American Society of Clinical Oncology, 2021-08)Abstract Purpose: We present a physician survey of the impact of 21-gene Breast Recurrence Score test results on treatment decisions in clinical practice in Latin America. Methods: This prospective survey enrolled ... -
IMT504 blocks allodynia in rats with spared nerve injury by promoting the migration of mesenchymal stem cells and by favoring an anti-inflammatory milieu at the injure nerve
(International Association for the Study of Pain, 2021-09)IMT504, a noncoding, non-CpG oligodeoxynucleotide, modulates pain-like behavior in rats undergoing peripheral nerve injury, through mechanisms that remain poorly characterized. Here, we chose the spared nerve injury model ... -
Drug-induced liver injury: A management position paper from the Latin American Association for Study of the liver
(Elsevier, 2021-09)Abstract Idiosyncratic drug-induced liver injury (DILI) caused by xenobiotics (drugs, herbals and dietary supplements) is an uncommon cause of liver disease presenting with a wide range of phenotypes and disease severity, ... -
Preeclampsia and COVID-19: results from the INTERCOVID prospective longitudinal study
(Elsevier, 2021-09)Abstract Background: It is unclear whether the suggested link between COVID-19 during pregnancy and preeclampsia is an independent association or if these are caused by common risk factors. Objective: This study aimed ... -
Is perineal hypermobility an independent predictor of obstructive defecation?
(Springer, 2021-09)Abstract Introduction and hypothesis: Symptoms of obstructed defecation (OD) and anatomical abnormalities of the posterior compartment are prevalent in urogynecological patients. The aim of this study was to determine ... -
Hepatitis C Virus Infection: What Are We Currently Doing in Latin America About WHO's Proposals for 2030?
(American Association for the Study of Liver Diseases, 2021-09)Hepatitis C virus (HCV) infection is a serious health problem worldwide. It has been estimated that it affects 1% of the global population, and most of these indi-viduals are unaware until the development ... -
El valor de la paternidad
(cuadernos para la formación sacerdotal permanente, 2021-10)Padres Se ha dicho que “hay un quiebre social en el proceso de hacer humanos a los humanos”; este punto es clave, es la base de cualquier análisis de la paternidad. En su sentido mas genérico, educar es mejorar al hombre4. -
The impact of hydroxychloroquine on obstetric outcomes in refractory obstetric antiphospholipid syndrome
(Elsevier, 2021-10)Abstract Background: The use of low-dose aspirin (LDA) and heparin has improved pregnancy outcomes in women with antiphospholipid syndrome (APS). However, 20-30% still have adverse outcomes despite treatment. Recent ... -
Minimally invasive treatment of AO B ankle fractures: Surgical technique and long-term outcomes
(Elsevier, 2021-10)Abstract Background: Ankle fractures are the most common traumatic bone injuries of the lower limb. Over 50% of ankle fractures occur at the syndesmosis level (type AO B). The goal of treatment is to achieve an anatomical ... -
'Real-life' experience with direct-acting antiviral agents for HCV after kidney transplant
(Elsevier, 2021-11)Abstract Introductions and objectives: The introduction of direct-acting antiviral (DAA) agents promises to change dramatically the management of hepatitis C in kidney transplant recipients, a patient group where the ... -
Impact of Public Health Policies on Alcohol-Associated Liver Disease in Latin America: An Ecological Multinational Study
(Lippincott, Williams & Wilkins [Commercial Publisher], 2021-11)Abstract Background and aims: Alcohol-associated liver disease (ALD) is the leading cause of liver-related mortality in Latin America, yet the impact of public health policies (PHP) on liver disease is unknown. We aimed ... -
Minimally Invasive Chevron Surgery and Bosch Percutaneous Osteotomy in Hallux Valgus Treatment. Midterm Results. Comparative Radiological Study
(Thieme Gruppe, 2021-11)Abstract Objective The purpose of the present study is to compare the radiological results of angular correction and its maintenance in the medium term between two minimally invasive techniques for the treatment of hallux ... -
Identification of optimal therapeutic window for steroid use in severe alcohol-associated hepatitis: A worldwide study
(Elsevier, 2021-11)Abstract Background & aims: Corticosteroids are the only effective therapy for severe alcohol-associated hepatitis (AH), defined by a model for end-stage liver disease (MELD) score >20. However, there are patients who may ... -
Reducing medication errors for adults in hospital settings
(Cochrane Collaboration, 2021-11)Abstract Background: Medication errors are preventable events that may cause or lead to inappropriate medication use or patient harm while the medication is in the control of the healthcare professional or patient. ... -
Outcomes of surgical treatment for isolated adrenal metastasis from non-small cell lung cancer
(Ecancermedicalscience, 2021-11)Abstract Objective: Long-term survival of patients who undergo surgical resection of isolated adrenal metastasis instead of nonsurgical treatment has shown higher values than those described for stage IVA. The primary ... -
Failure in all steps of hepatocellular carcinoma surveillance process is frequent in daily practice
(Elsevier, 2021-11)Abstract Introduction and objectives: Failures at any step in the hepatocellular carcinoma (HCC) surveillance process can result in HCC diagnostic delays and associated worse prognosis. We aimed to estimate the prevalence ... -
Targeting ADCC: A different approach to HER2 breast cancer in the immunotherapy era
(Elsevier, 2021-12)Abstract The clinical outcome of patients with human epidermal growth factor receptor 2 (HER2) amplified breast carcinoma (BC) has improved with the development of anti-HER2 targeted therapies. However, patients can ... -
The tale of TILs in breast cancer: A report from The International Immuno-Oncology Biomarker Working Group
(Nature Research, 2021-12)Abstract The advent of immune-checkpoint inhibitors (ICI) in modern oncology has significantly improved survival in several cancer settings. A subgroup of women with breast cancer (BC) has immunogenic infiltration of ... -
Galectin-1 and Galectin-3 Expression in Lesional Skin of Patients With Systemic Sclerosis-Association With Disease Severity
(Lippincott, Williams & Wilkins, 2021-12)Abstract Galectin-1 (Gal-1) and galectin-3 (Gal-3) are carbohydrate-binding proteins involved in normal processes, autoimmunity, and cancer. Increased serum Gal-3 levels in scleroderma were associated with active disease, ... -
Ibero-American Society of Interventionism (SIDI) and the Spanish Society of Vascular and Interventional Radiology (SERVEI) Standard of Practice (SOP) for the Management of Inferior Vena Cava Filters in the Treatment of Acute Venous Thromboembolism
(MDPI, 2021-12)Abstract Objectives: to present an interventional radiology standard of practice on the use of inferior vena cava filters (IVCFs) in patients with or at risk to develop venous thromboembolism (VTE) from the Iberoamerican ...