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Liver transplantation for hepatocellular carcinoma: evaluation of the alpha-fetoprotein model in a multicenter cohort from Latin America.
(John Wiley & Sons A/S, 2016-05-05)
BACKGROUND & AIMS:
The French alpha-fetoprotein (AFP) model has recently shown superior results compared to Milan criteria (MC) for prediction of hepatocellular carcinoma (HCC) recurrence after liver transplantation (LT) ...
Chronic hyperprolactinemia evoked by disruption of lactotrope dopamine D2 receptors impacts on liver and adipocyte genes related to glucose and insulin balance.
(American Physiological Society, 2016-11-01)
We studied the impact of high prolactin titers on liver and adipocyte gene expression related to glucose and insulin homeostasis in correlation with obesity onset. To that end we used mutant female mice that selectively ...
International variations in application of the best-interest standard across the age spectrum.
(Springer Nature [academic journals on nature.com, 2016-10-13)
OBJECTIVE:
Ethically and legally, assertions that resuscitation is in a patient's best interest should be inversely correlated with willingness to forego intensive care (and accept comfort care) at the surrogate's request. ...
Dorsal root ganglion neurons and tyrosine hydroxylase--an intriguing association with implications for sensation and pain.
(International Association for the Study of Pain, 2016-02-01)
Tyrosine hydroxylase (TH) is a rate-limiting enzyme broadly expressed in noradrenergic and
dopaminergic neurons in the central nervous system [57,70]. TH is also expressed by peripheral
sympathetic neurons [98] as well ...