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Diseño metodológico de un estudio de investigación
(FUNDASAMIN (Fundación para la Salud Materno Infantil), 2017-12-01)
La investigación comprende un conjunto de sistemáticas
que permiten dar respuesta a preguntas disímiles y
que pueden estar en relación a datos objetivos de la
realidad o bien a las percepciones y experiencias que
resultan ...
Predictive models for recurrence risk of hepatocellular carcinoma after liver transplantation: Still an unmet need.
(Wiley, 2017-05-01)
Recurrence of hepatocellular carcinoma (HCC) after liver transplanta-tion (LT) is a frightening issue. It is considered a systemic advanced stage with poor survival rate from the time of its diagnosis, with few therapeutic ...
The Latin American experience of allografting patients with severe aplastic anaemia: real-world data on the impact of stem cell source and ATG administration in HLA-identical sibling transplants
(Springer Nature [academic journals on nature.com], 2017-01-01)
We studied 298 patients with severe aplastic anaemia (SAA) allografted in four Latin American countries. The source of cells was bone marrow (BM) in 94 patients and PBSCs in 204 patients. Engraftment failed in 8.1% of ...
Transforming growth factor-β1 functional polymorphisms in myeloablative sibling hematopoietic stem cell transplantation
(Springer Nature [academic journals on nature.com], 2017-05-01)
Hematopoietic stem cell transplantation (HSCT) with sibling donors (s.d.) is a life-saving intervention for patients with hematological malignancies. Numerous genetic factors have a role in transplant outcome. Several ...
Latin America: the next region for haematopoietic transplant progress.
(Springer Nature [academic journals on nature.com], 2017-05-01)
Haematopoietic cell transplant activity in the 28 countries comprising Latin America is poorly defined. We conducted a voluntary survey of members of the Latin American Bone Marrow Transplantation Group regarding transplant ...
Vulvar Langerhans cell histiocytosis and thalidomide: an effective treatment option
(Wiley, 2017-10-25)
Langerhans cell histiocytosis (LCH) is a disease characterized
by clonal proliferation and a pathological infiltration of Langerhans cells in one or more organs, in which almost every tissue
may be involved. Its incidence ...
Spinal neuropeptide expression and neuropathic behavior in the acute and chronic phases after spinal cord injury: Effects of progesterone administration.
(Elsevier Inc. All rights reserved., 2017-02)
Patients with spinal cord injury (SCI) develop chronic pain that severely compromises their quality of life. We have previously reported that progesterone (PG), a neuroprotective steroid, could offer a promising therapeutic ...
Systemic Transplantation of Bone Marrow Mononuclear Cells Promotes Axonal Regeneration and Analgesia in a Model of Wallerian Degeneration
(Lippincott, Williams & Wilkins, 2017-07)
Background
Reinnervation timing after nerve injury is critical for favorable axonal regeneration, remyelination, and clinical improvement. Considering bone marrow mononuclear cells (BMMC) are easily obtained and readily ...
Ethical dilemmas associated with clinicians' decisions about treatment in critically ill infants born in Córdoba, Argentina.
(SAGE Publications, 2017-01-23)
The objective of this article is to examine end of life decisions made by neonatologists of Córdoba, Argentina. An anonymous questionnaire was designed to investigate neonatologists’ decisions on when to initiate or withdraw ...
En las fronteras de la ética de la investigación clínica: ajustando las normas al progreso.
(Revista Argentina de Cardiología, 2017-06-01)
Es claro que las normas pueden ser buenas, regulares o
malas. Dada la lógica normativa y burocrática, no hay
mucho énfasis ni investigación sobre las malas normas
en investigación clínica y su impacto en la producción ...