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dc.contributor.authorWiersba, Valeria.
dc.contributor.authorManselle, Montana.
dc.contributor.authorVeigas, Florencia.
dc.contributor.authorEt al.
dc.date.accessioned2023-07-03T15:51:00Z
dc.date.available2023-07-03T15:51:00Z
dc.date.issued2021
dc.identifier.citationMedicina (B Aires) . 2021;81(5):683-687.es
dc.identifier.issn1669-9106
dc.identifier.urihttps://riu.austral.edu.ar/handle/123456789/2207
dc.identifier.urihttps://www.medicinabuenosaires.com/PMID/34633939.pdf
dc.descriptionDisponible en: https://www.medicinabuenosaires.com/PMID/34633939.pdfes
dc.description.abstractAbstract in English, Spanish The rapid spread of the SARS-CoV-2, the causative agent of the emergent pandemic disease COVID-19, requires the urgent commitment of the immunology community to understand the adaptive immune response developed by COVID-19 convalescent patients and individuals vaccinated with different strategies and schemes, with the ultimate goal of implementing and optimizing health care and prevention policies. Currently, assessment of SARS-CoV-2-specific immunity is mainly focused on the measurement of the antibody titers and analysis of their neutralizing capacity. However, a considerable proportion of individuals lack humoral responses or show a progressive decline of SARS-CoV-2-specific neutralizing antibodies. In order to study the cellular response of convalescent patients and vaccinated individuals, we have developed the "COVID-T Platform", an optimized strategy to study SARS-CoV-2-specific T cell responses. This platform allows assessment of the nature, magnitude and persistence of antigen-specific T-cell immunity in COVID-19-convalescent patients and vaccinated individuals. Moreover, it gives the opportunity to study cellular responses against emerging coronavirus variants and to identify individuals with cross-reactive immunity against seasonal coronaviruses. Keywords: COVID-19; SARS-CoV-2; T cells; immunity; vaccination.es
dc.language.isoeses
dc.publisherMedicina Buenos Aireses
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectCOVID-19.es
dc.subjectSARS-CoV-2.es
dc.subjectT cells.es
dc.titleA functional platform to monitor SARS-CoV-2-specific T cell responses in vaccinated individuals and COVID-19 recovered patientses
dc.typeArticlees


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Attribution-NonCommercial-NoDerivatives 4.0 Internacional
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivatives 4.0 Internacional