Browsing by Author "Gallo, Juan E."
Now showing items 1-7 of 7
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Corneal Neovascularization: A Combined Approach of Bevacizumab and Suramin Showed Increased Antiangiogenic Effect Through Downregulation of BFGF and P2X2
Lopez, Emiliano S.; Ortiz, Gustavo.; Potilinski, Constanza.; Croxatto, Oscar.; Gallo, Juan E. (Current Eye Research, 2017-12-21)ABSTRACT Purpose: The objective is to analyze the antiangiogenic mechanism of suramab, a pharmaceutical compound of bevacizumab and suramin, in a rabbit model of corneal angiogenesis. Material and Methods: Corneal ... -
Elucidating the mechanism of action of alpha-1-antitrypsin using retinal pigment epithelium cells exposed to high glucose. Potential use in diabetic retinopathy
Potilinski, María.; Ortiz, Gustavo.; Salica, Juan.; Lopez, Emiliano S.; Fernandez, Mariano.; Chuluyan, Eduardo.; Gallo, Juan E. (Potilinski et a, 2020-02-07)Abstract Background: Alpha-1-antitrypsin is a protein involved in avoidance of different processes that are seen in diabetic retinopathy pathogenesis. These processes include apoptosis, extracellular matrix remodeling and ... -
Ethical dilemmas associated with clinicians' decisions about treatment in critically ill infants born in Córdoba, Argentina.
Silberberg, Agustín.; Gallo, Juan E. (SAGE Publications, 2017-01-23)The objective of this article is to examine end of life decisions made by neonatologists of Córdoba, Argentina. An anonymous questionnaire was designed to investigate neonatologists’ decisions on when to initiate or withdraw ... -
Evaluation of the Performance of an Ophthalmic Thermosensitive Hydrogel Containing Combination of Suramin and Bevacizumab.
Quinteros, Daniela A.; Lopez, Emiliano S.; Couto, Juan L.; Maletto, Belkys A.; Allemandi, Daniel A.; Palma, Santiago D.; Gallo, Juan E. (Bentham Science Publishers, 2016)Suramab (SUM) is a new pharmaceutical combination made up of suramine (SUR) and bevacizumab (BVM), which showed a high synergistic effect when administered jointly. As the pharmaceutical vehicle, poloxamer aqueous dispersions ... -
Evaluation of the Performance of an Ophthalmic Thermosensitive Hydrogel Containing Combination of Suramin and Bevacizumab.
Quinteros, Daniela.; Lopez, Emiliano S.; Couto, Juan L.; Maletto, Belkys A.; Allemandi, Daniel A.; Palma, Santiago D.; Gallo, Juan E. (Bentham Science Publishers, 2016)Suramab (SUM) is a new pharmaceutical combination made up of suramine (SUR) and bevacizumab (BVM), which showed a high synergistic effect when administered jointly. As the pharmaceutical vehicle, poloxamer aqueous dispersions ... -
Multiprong control of glioblastoma multiforme invasiveness: blockade of pro-inflammatory signaling, anti-angiogenesis, and homeostasis restoration
Gallo, Juan E.; Bazan, Nicolas.; Reid, Madigan.; Et al. (Springer, 2021-09)Abstract Glioblastoma multiforme (GBM) is the most invasive type of glial tumor with poor overall survival, despite advances in surgical resection, chemotherapy, and radiation. One of the main challenges in treating GBM ... -
Possible neuroprotective role of P2X2 in the retina of diabetic rats.
Mancini, Jorge.; Ortiz, Gustavo.; Potilinski, Constanza.; Salica, Juan.; Lopez, Emiliano S.; Croxatto, Oscar.; Gallo, Juan E. (Springer Nature, 2018-04-12)Abstract Background: Purinergic receptors are expressed in diferent tissues including the retina. These receptors are involved in processes like cell growth, proliferation, activation and survival. ATP is the major ...