Browsing Investigación básica. by Issue Date
Now showing items 21-40 of 79
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Congenital Bladder Prolapse Through a Patent Urachus: Two Institutions' Experience
(2021-03)Abstract We describe our experience in 2 institutions handling bladder prolapse through a patent urachus (PU), together with a brief review of published literature. Case 1: A term neonate with congenital prolapsed bladder ... -
Development of an Improved Guanidine-Based Rac1 Inhibitor with in vivo Activity against Non-Small Cell Lung Cancer
(Wiley, 2021-03)Abstract The Rho GTPase Rac1 is involved in the control of cytoskeleton reorganization and other fundamental cellular functions. Aberrant activity of Rac1 and its regulators is common in human cancer. In particular, ... -
HERC1 Regulates Breast Cancer Cells Migration and Invasion
(MDPI, 2021-03)Abstract Tumor cell migration Tumor cell migration and invasion into adjacent tissues is one of the hallmarks of cancer and the first step towards secondary tumors formation, which represents the leading cause of ... -
USP19 modulates cancer cell migration and invasion and acts as a novel prognostic marker in patients with early breast cancer
(Springer Nature, 2021-03)Abstract Tumor cell dissemination in cancer patients is associated with a significant reduction in their survival and quality of life. The ubiquitination pathway plays a fundamental role in the maintenance of protein ... -
4-methylumbelliferone-mediated polarization of M1 macrophages correlate with decreased hepatocellular carcinoma aggressiveness in mice
(Nature Research, 2021-03-01)Hepatocellular carcinoma (HCC) arises in the setting of advanced liver fibrosis, a dynamic and complex inflammatory disease. The tumor microenvironment (TME) is a mixture of cellular components including cancer cells, ... -
Consensus on the Treatment and Follow-Up for Metastatic Castration-Resistant Prostate Cancer: A Report From the First Global Prostate Cancer Consensus Conference for Developing Countries (PCCCDC)
(American Society of Clinical Oncology, 2021-04)Abstract Purpose: To present a summary of the recommendations for the treatment and follow-up for metastatic castration-resistant prostate cancer (mCRPC) as acquired through a questionnaire administered to 99 physicians ... -
Consensus on Treatment and Follow-Up for Biochemical Recurrence in Castration-Sensitive Prostate Cancer: A Report From the First Global Prostate Cancer Consensus Conference for Developing Countries
(American Society of Clinical Oncology, 2021-04)Abstract Purpose: To present a summary of the treatment and follow-up recommendations for the biochemical recurrence in castration-sensitive prostate cancer (PCa) acquired through a questionnaire administered to 99 PCa ... -
CSIS: Proposal for a New Combined Screening Interpretation Score for Patients with Mild Cognitive Impairment
(Taylor and Francis Group, 2021-04)Abstract Introduction: It is essential to have sensitive, economical and quick cognitive screening tools for early detection of Mild Cognitive Impairment (MCI). The objective of the present study was to assess a new way ... -
Optical clearing reveals TNBS-induced morphological changes of VGLUT2-positive nerve fibers in mouse colorectum
(American Physiological Society, 2021-04)Abstract Colorectal hypersensitivity and sensitization of both mechanosensitive and mechanically insensitive afferents develop after intracolonic instillation of 2,4,6-trinitrobenzenesulfonic acid (TNBS) in the mouse, a ... -
Budget impact analysis of using procalcitonin to optimize antimicrobial treatment for patients with suspected sepsis in the intensive care unit and hospitalized lower respiratory tract infections in Argentina
(Public Library of Science, 2021-04)Abstract Background: Inappropriate antibiotic use represents a major global threat. Sepsis and bacterial lower respiratory tract infections (LRTIs) have been linked to antimicrobial resistance, carrying important consequences ... -
Clinical characteristics and evolution of hematological patients and COVID-19 in Argentina: a report from the Argentine Society of Hematology
(Medicina Buenos Aires, 2021-05)Abstract in English, Spanish Individuals with malignancies and COVID-19 have a lower survival compared with the general population. However, the information about the impact of COVID-19 on the whole hematological population ... -
New insights into oxidative stress and immune mechanisms involved in age-related macular degeneration tackled by novel therapies
(Elsevier, 2021-05)Abstract The prevalence of age-related macular degeneration (AMD) has increased in the last years. Although anti-VEGF agents have improved the prognosis of exudative AMD, dry AMD has still devastating effects on elderly ... -
Current Status of Training and Certification for Congenital Heart Surgery Around the World: Proceedings of the Meetings of the Global Council on Education for Congenital Heart Surgery of the World Society for Pediatric and Congenital Heart Surgery
(SAGE Publications, 2021-05)Abstract The optimal training of the highly specialized congenital heart surgeon is a long and complex process, which is a significant challenge in most parts of the world. The World Society for Pediatric and Congenital ... -
Acceleration of TAA-Induced Liver Fibrosis by Stress Exposure Is Associated with Upregulation of Nerve Growth Factor and Glycopattern Deviations
(MDPI [Commercial Publisher], 2021-05-01)Abstract Liver fibrosis results from many chronic injuries and may often progress to cirrhosis and hepatocellular carcinoma (HCC). In fact, up to 90% of HCC arise in a cirrhotic liver. Conversely, stress is implicated in ... -
Breast milk production and emotional state in mothers of very low birth weight infants
(sociedad argentina de pediatria, 2021-06)Abstract in English, Spanish Introduction: There is little evidence regarding the influence of emotional variables on breastfeeding among mothers of very low birth weight infants (VLBWIs). The objective of this study was ... -
Assessing the impact of COVID-19 on liver cancer management (CERO-19)
(Elsevier, 2021-06)Abstract Background & aims: The coronavirus disease 2019 (COVID-19) pandemic has posed unprecedented challenges to healthcare systems and it may have heavily impacted patients with liver cancer (LC). Herein, we evaluated ... -
COVID-19 in multiple sclerosis and neuromyelitis optica spectrum disorder patients in Latin America: COVID-19 in MS and NMOSD patients in LATAM
(Elsevier, 2021-06)Abstract Background: There is no data regarding COVID-19 in Multiple Sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD) patients in Latin America. Objective: The objective of this study was to describe ... -
An Ethical Pathway to Quality of Life in Critically Ill Newborns
(Taylor and Francis Group [Commercial Publisher] Routledge [Imprint], 2021-06-01)Abstract Advances in perinatology have permitted the survival of fragile neonates. Quality of life (QoL) has been considered a key element in medical decision-making. In this review we analyse the role of QoL regarding ... -
Alcohol consumption leads to loss of healthy life, but the ADH1B*2 allele may still protect from NASH
(AME Publishing [Commercial Publisher], 2021-06-01)La enfermedad del hígado graso no alcohólico (NAFLD, por sus siglas en inglés) es ahora la causa más común de enfermedad hepática crónica en todo el mundo, afecta a casi una cuarta parte de la población mundial ( 1 , 2 ) ... -
Acute peritoneal dialysis, complications and outcomes in 389 children with STEC-HUS: a multicenter experience
(Springer [Commercial Publisher], 2021-06-01)Abstract Background: Management of acute kidney injury (AKI) in children with hemolytic uremic syndrome induced by a Shiga toxin-producing Escherichia coli infection (STEC-HUS) is supportive; however, 40 to 60% of cases ...