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Corneal Neovascularization: A Combined Approach of Bevacizumab and Suramin Showed Increased Antiangiogenic Effect Through Downregulation of BFGF and P2X2
(Current Eye Research, 2017-12-21)
ABSTRACT
Purpose: The objective is to analyze the antiangiogenic mechanism of suramab, a pharmaceutical compound of bevacizumab and suramin, in a rabbit model of corneal angiogenesis.
Material and Methods: Corneal ...
The Latin American experience of allografting patients with severe aplastic anaemia: real-world data on the impact of stem cell source and ATG administration in HLA-identical sibling transplants
(Springer Nature [academic journals on nature.com], 2017-01-01)
We studied 298 patients with severe aplastic anaemia (SAA) allografted in four Latin American countries. The source of cells was bone marrow (BM) in 94 patients and PBSCs in 204 patients. Engraftment failed in 8.1% of ...
Risk factors for advanced resuscitation in term and near-term infants: a case-control study.
(BMJ Publishing Group Limited., 2017-01-01)
OBJECTIVE:
(1) To determine which antepartum and/or intrapartum factors are associated with the need for advanced neonatal resuscitation (ANR) at birth in infants with gestational age (GA) ≥34 weeks. (2) To develop a risk ...
Transforming growth factor-β1 functional polymorphisms in myeloablative sibling hematopoietic stem cell transplantation
(Springer Nature [academic journals on nature.com], 2017-05-01)
Hematopoietic stem cell transplantation (HSCT) with sibling donors (s.d.) is a life-saving intervention for patients with hematological malignancies. Numerous genetic factors have a role in transplant outcome. Several ...
Ethical dilemmas associated with clinicians' decisions about treatment in critically ill infants born in Córdoba, Argentina.
(SAGE Publications, 2017-01-23)
The objective of this article is to examine end of life decisions made by neonatologists of Córdoba, Argentina. An anonymous questionnaire was designed to investigate neonatologists’ decisions on when to initiate or withdraw ...