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IMT504 blocks allodynia in rats with spared nerve injury by promoting the migration of mesenchymal stem cells and by favoring an anti-inflammatory milieu at the injure nerve
(International Association for the Study of Pain, 2021-09)
IMT504, a noncoding, non-CpG oligodeoxynucleotide, modulates pain-like behavior in rats undergoing peripheral nerve injury, through mechanisms that remain poorly characterized. Here, we chose the spared nerve injury model ...
'Real-life' experience with direct-acting antiviral agents for HCV after kidney transplant
(Elsevier, 2021-11)
Abstract
Introductions and objectives: The introduction of direct-acting antiviral (DAA) agents promises to change dramatically the management of hepatitis C in kidney transplant recipients, a patient group where the ...
Factors Associated with Survival and Survival without Major Morbidity in Very Preterm Infants in Two Neonatal Networks: SEN1500 and NEOCOSUR
(Karger, 2021-02)
Abstract
Introduction: Very low-birth weight (VLBW) infants represent a high-risk population for morbidity and mortality in the neonatal period. Variability in practices and outcomes between centers has been acknowledged. ...
Drug-induced liver injury: A management position paper from the Latin American Association for Study of the liver
(Elsevier, 2021-09)
Abstract
Idiosyncratic drug-induced liver injury (DILI) caused by xenobiotics (drugs, herbals and dietary supplements) is an uncommon cause of liver disease presenting with a wide range of phenotypes and disease severity, ...
Targeting ADCC: A different approach to HER2 breast cancer in the immunotherapy era
(Elsevier, 2021-12)
Abstract
The clinical outcome of patients with human epidermal growth factor receptor 2 (HER2) amplified breast carcinoma (BC) has improved with the development of anti-HER2 targeted therapies. However, patients can ...
Severe Cutaneous Adverse Reactions to Drugs in Latin America: The RACGRAD Study
(ESMON PUBLICIDAD, 2021-07)
Abstract
Background and objective: Severe cutaneous adverse reactions to drugs (SCARs) are associated with high morbidity and mortality and with sequelae. Objective: To characterize patients with SCARs in 8 health care ...
Prospective Latin American cohort evaluating outcomes of patients with COVID-19 and abnormal liver tests on admission
(Elsevier, 2021-03)
Abstract
Introduction & objectives: The independent effect of liver biochemistries as a prognostic factor in patients with COVID-19 has not been completely addressed. We aimed to evaluate the prognostic value of abnormal ...
Liver transplantation for hepatocellular carcinoma: impact of expansion criteria in a multicenter cohort study from a high waitlist mortality region
(Wiley, 2021-01)
Abstract
This study aimed to compare liver transplantation (LT) outcomes and evaluate the potential rise in numbers of LT candidates with hepatocellular carcinoma (HCC) of different allocation policies in a high waitlist ...
The impact of hydroxychloroquine on obstetric outcomes in refractory obstetric antiphospholipid syndrome
(Elsevier, 2021-10)
Abstract
Background: The use of low-dose aspirin (LDA) and heparin has improved pregnancy outcomes in women with antiphospholipid syndrome (APS). However, 20-30% still have adverse outcomes despite treatment. Recent ...
Open intrauterine repair of spina bifida aperta: Historical aspects, current availability, and clinical outcomes from the Latin American Spina Bifida Consortium
(Wiley, 2021-07)
Abstract
Objective: To determine the historical aspects, current availability, and clinical outcomes of open intrauterine repair of spina bifida aperta (IRSBA) in Spanish-speaking Latin American countries.
Methods: ...