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IMT504 blocks allodynia in rats with spared nerve injury by promoting the migration of mesenchymal stem cells and by favoring an anti-inflammatory milieu at the injure nerve
(International Association for the Study of Pain, 2021-09)
IMT504, a noncoding, non-CpG oligodeoxynucleotide, modulates pain-like behavior in rats undergoing peripheral nerve injury, through mechanisms that remain poorly characterized. Here, we chose the spared nerve injury model ...
Neuroactive steroids, nociception and neuropathic pain: A flashback to go forward.
(Elsevier Inc. All rights reserved., 2016-04-11)
The present review discusses the potential role of neurosteroids / neuroactive steroids in
the regulation of nociceptive and neuropathic pain, and recapitulates the current
knowledge on the main mechanisms involved in ...
Spinal neuropeptide expression and neuropathic behavior in the acute and chronic phases after spinal cord injury: Effects of progesterone administration.
(Elsevier Inc. All rights reserved., 2017-02)
Patients with spinal cord injury (SCI) develop chronic pain that severely compromises their quality of life. We have previously reported that progesterone (PG), a neuroprotective steroid, could offer a promising therapeutic ...