Search
Now showing items 31-40 of 56
Development of an Improved Guanidine-Based Rac1 Inhibitor with in vivo Activity against Non-Small Cell Lung Cancer
(Wiley, 2021-03)
Abstract
The Rho GTPase Rac1 is involved in the control of cytoskeleton reorganization and other fundamental cellular functions. Aberrant activity of Rac1 and its regulators is common in human cancer. In particular, ...
Limitation of life-sustaining treatment in NICU: Physicians' beliefs and attitudes in the Buenos Aires region
(Elsevier, 2020-03)
Abstract
Objective: To explore the ethical beliefs and attitudes of Argentinean neonatologists regarding limitation of life-sustaining treatment (LST) for very sick infants.
Methods: We used an anonymous questionnaire ...
An inflammatory aging clock (iAge) based on deep learning tracks multimorbidity, immunosenescence, frailty and cardiovascular aging
(Nature Research [Commercial Publisher], 2021-07)
Abstract
While many diseases of aging have been linked to the immunological system, immune metrics
capable of identifying the most at-risk individuals are lacking. From the blood immunome of
1,001 individuals aged 8–96 ...
Clinical presentation and outcomes of the first patients with COVID-19 in Argentina: Results of 207079 cases from a national database
(Public Library of Science, 2021-02)
Abstract
Background: There is limited evidence on the clinical characteristics of SARS-CoV-2 infection in Latin America. We present findings from a nationwide study in Argentina.
Research question: What is disease ...
Clinical next generation sequencing in developmental and epileptic encephalopathies: Diagnostic relevance of data re-analysis and variants re-interpretation
(Elsevier, 2021-12)
Abstract
Developmental and epileptic encephalopathies (DEE) are complex pediatric epilepsies, in which heterogeneous pathogenic factors play an important role. Next-generation-sequencing based tools have shown excellent ...
Controversies during the COVID-19 pandemic
(Fundación Revista Medicina, 2021)
Abstract in English, Spanish
The COVID-19 pandemic has had an impact on public health and the global economy. The objective of this document was to update, according to the available evidence, the management of some basic ...
Consensus on the Treatment and Follow-Up for Metastatic Castration-Resistant Prostate Cancer: A Report From the First Global Prostate Cancer Consensus Conference for Developing Countries (PCCCDC)
(American Society of Clinical Oncology, 2021-04)
Abstract
Purpose: To present a summary of the recommendations for the treatment and follow-up for metastatic castration-resistant prostate cancer (mCRPC) as acquired through a questionnaire administered to 99 physicians ...
Consensus on Treatment and Follow-Up for Biochemical Recurrence in Castration-Sensitive Prostate Cancer: A Report From the First Global Prostate Cancer Consensus Conference for Developing Countries
(American Society of Clinical Oncology, 2021-04)
Abstract
Purpose: To present a summary of the treatment and follow-up recommendations for the biochemical recurrence in castration-sensitive prostate cancer (PCa) acquired through a questionnaire administered to 99 PCa ...
Congenital Bladder Prolapse Through a Patent Urachus: Two Institutions' Experience
(2021-03)
Abstract
We describe our experience in 2 institutions handling bladder prolapse through a patent urachus (PU), together with a brief review of published literature. Case 1: A term neonate with congenital prolapsed bladder ...