Browsing Facultad de Ciencias Biomédicas -FCB- by Author "Leiguarda, Candelaria."
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Intrathecal Administration of an Anti-nociceptive Non-CpG Oligodeoxynucleotide Reduces Glial Activation and Central Sensitization
Leiguarda, Candelaria.; Villar, Marcelo.; Brumovsky, Pablo.; Et al. (Springer, 2021-12)Abstract Inflammatory pain associates with spinal glial activation and central sensitization. Systemic administration of IMT504, a non-CpG oligodeoxynucleotide originally designed as an immunomodulator, exerts remarkable ... -
Transcript Expression of Vesicular Glutamate Transporters in Rat Dorsal Root Ganglion and Spinal Cord Neurons: Impact of Spinal Blockade during Hindpaw Inflammation
Leiguarda, Candelaria.; McCarthy, Carly J.; Casadei, Mailin.; Et al. (American Chemical Society, 2020-09)Abstract Studies in mouse, and to a lesser extent in rat, have revealed the neuroanatomical distribution of vesicular glutamate transporters (VGLUTs) and begun exposing the critical role of VGLUT2 and VGLUT3 in pain ...