Browsing Facultad de Ciencias Biomédicas -FCB- by Author "Aquino, Jorge."
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GABAergic Mechanisms Can Redress the Tilted Balance between Excitation and Inhibition in Damaged Spinal Networks
Mazzone, Graciela.; Aquino, Jorge.; Nistri, Andrea.; Et al. (Springer, 2021-08)Abstract Correct operation of neuronal networks depends on the interplay between synaptic excitation and inhibition processes leading to a dynamic state termed balanced network. In the spinal cord, balanced network activity ... -
Nicotine Neurotoxicity Involves Low Wnt1 Signaling in Spinal Locomotor Networks of the Postnatal Rodent Spinal Cord
Mazzone, Graciela.; Kaur, Jaspreet.; Aquino, Jorge.; Et al. (MDPI, 2021-09)Abstract The postnatal rodent spinal cord in-vitro is a useful model to investigate early pathophysiological changes after injury. While low dose nicotine (1 µM) induces neuroprotection, how higher doses affect spinal ...