Centro Académico de Salud (CAS): Recent submissions
Now showing items 101-120 of 459
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Hepatitis B virus vaccine and chronic kidney disease. The advances
(Sociedad española de nefrología, 2021-03)Abstract Background: Hepatitis B is an important agent of liver disease in patients with chronic kidney disease and chronic HBV infection promotes the development of CKD in the adult general population. Patients with CKD ... -
Galectin-1 and Galectin-3 Expression in Lesional Skin of Patients With Systemic Sclerosis-Association With Disease Severity
(Lippincott, Williams & Wilkins, 2021-12)Abstract Galectin-1 (Gal-1) and galectin-3 (Gal-3) are carbohydrate-binding proteins involved in normal processes, autoimmunity, and cancer. Increased serum Gal-3 levels in scleroderma were associated with active disease, ... -
GABAergic Mechanisms Can Redress the Tilted Balance between Excitation and Inhibition in Damaged Spinal Networks
(Springer, 2021-08)Abstract Correct operation of neuronal networks depends on the interplay between synaptic excitation and inhibition processes leading to a dynamic state termed balanced network. In the spinal cord, balanced network activity ... -
Functional and druggability analysis of the SARS-CoV-2 proteome
(Elsevier, 2021-01)Abstract The infectious coronavirus disease (COVID-19) pandemic, caused by the coronavirus SARS-CoV-2, appeared in December 2019 in Wuhan, China, and has spread worldwide. As of today, more than 46 million people have ... -
Functional anatomy of idiomatic expressions
(Springer, 2021-07)Abstract Idiomatic expressions (IE) are groups of words whose meaning is different from the sum of its components. Neural mechanisms underlying their processing are still debated, especially regarding lateralization, main ... -
From textbook to patient: a practical guide to train the end-to-side microvascular anastomosis
(T Taylor and Francis Group, 2023-02)Abstract Microvascular anastomosis is one of the most challenging neurosurgical techniques. Mastering this technique allows to perform intracranial bypass with arteries of small caliber usually placed in deep narrow ... -
Frequency, Risk Factors, Clinical Characteristics, and Outcomes of Spontaneous Pneumothorax in Patients With Coronavirus Disease 2019: A Case-Control, Emergency Medicine-Based Multicenter Study
(Elsevier, 2021-03)Abstract Background: Recent reports of patients with coronavirus disease 2019 (COVID-19) developing pneumothorax correspond mainly to case reports describing mechanically ventilated patients. The real incidence, clinical ... -
Feeding difficulties in children and adolescents with spinal muscular atrophy type 2
(Elsevier, 2021-02)Abstract Disease course of feeding difficulties in spinal muscular atrophy type 2 is not well documented. Disease-modifying therapies rapidly change the trajectory of motor function and survival in spinal muscular atrophy, ... -
Failure in all steps of hepatocellular carcinoma surveillance process is frequent in daily practice
(Elsevier, 2021-11)Abstract Introduction and objectives: Failures at any step in the hepatocellular carcinoma (HCC) surveillance process can result in HCC diagnostic delays and associated worse prognosis. We aimed to estimate the prevalence ... -
Factors Associated with Survival and Survival without Major Morbidity in Very Preterm Infants in Two Neonatal Networks: SEN1500 and NEOCOSUR
(Karger, 2021-02)Abstract Introduction: Very low-birth weight (VLBW) infants represent a high-risk population for morbidity and mortality in the neonatal period. Variability in practices and outcomes between centers has been acknowledged. ... -
Evaluation of Silicone Fluids and Resins as CO2 Thickeners for Enhanced Oil Recovery Using a Computational and Experimental Approach
(American Chemical Society [Society Publisher], 2021-09)Abstract CO2 thickeners have the potential to be a game changer for enhanced oil recovery, carbon capture utilization and storage, and hydraulic fracturing. Thickener design is challenging due to polymers' low solubility ... -
Exploring the Relationship between Shared Decision-Making, Patient-Centered Medicine, and Evidence-Based Medicine
(SAGE Publications, 2021-08)Abstract Shared decision-making is a possible link between the best of patient-centered medicine and evidence-based medicine. This article seeks to describe the link between them. It discusses to what extent the integration ... -
Editorial: biomarkers in HBV and prediction of treatment response
(Wiley, 2021-01)Hepatitis B cure is clinically defined as persistently undetectable HBsAg and hepatitis B virus (HBV) DNA in serum, with or without seroconversion to hepatitis B surface antibody (anti-HBs). ... -
Drug-induced liver injury: A management position paper from the Latin American Association for Study of the liver
(Elsevier, 2021-09)Abstract Idiosyncratic drug-induced liver injury (DILI) caused by xenobiotics (drugs, herbals and dietary supplements) is an uncommon cause of liver disease presenting with a wide range of phenotypes and disease severity, ... -
dockECR: Open consensus docking and ranking protocol for virtual screening of small molecules
(Elsevier, 2021-12)Abstract The development of open computational pipelines to accelerate the discovery of treatments for emerging diseases allows finding novel solutions in shorter periods of time. Consensus molecular docking is one of ... -
Diverse cellular origins of adult blood vascular endothelial cells
(Elsevier, 2021-09)Abstract During embryonic stages, vascular endothelial cells (ECs) originate from the mesoderm, at specific extraembryonic and embryonic regions, through a process called vasculogenesis. In the adult, EC renewal/replacement ... -
Direct-acting antiviral treatment failure in genotype 2 hepatitis C chronic infection
(Wiley, 2021-02)Comment J Viral Hepat . 2021 Feb;28(2):446-447. doi: 10.1111/jvh.13433. Epub 2020 Nov 18. Direct-acting antiviral treatment failure in genotype 2 hepatitis C chronic infection Ezequiel Ridruejo 1 2 3, Federico Piñero 2 ... -
Diabetes mellitus, maternal adiposity, and insulin-dependent gestational diabetes are associated with COVID-19 in pregnancy: the INTERCOVID study
(Elsevier, 2022-07)Abstract Background: Among nonpregnant individuals, diabetes mellitus and high body mass index increase the risk of COVID-19 and its severity. Objective: This study aimed to determine whether diabetes mellitus and high ... -
Development of an Improved Guanidine-Based Rac1 Inhibitor with in vivo Activity against Non-Small Cell Lung Cancer
(Wiley, 2021-03)Abstract The Rho GTPase Rac1 is involved in the control of cytoskeleton reorganization and other fundamental cellular functions. Aberrant activity of Rac1 and its regulators is common in human cancer. In particular, ... -
Current Status of Training and Certification for Congenital Heart Surgery Around the World: Proceedings of the Meetings of the Global Council on Education for Congenital Heart Surgery of the World Society for Pediatric and Congenital Heart Surgery
(SAGE Publications, 2021-05)Abstract The optimal training of the highly specialized congenital heart surgeon is a long and complex process, which is a significant challenge in most parts of the world. The World Society for Pediatric and Congenital ...