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The early onset of type 1 autoimmune hepatitis has a strong genetic influence: role of HLA and KIR genes.
(Springer Nature Switzerland AG. Springer is part of Springer Nature, 2016-02-18)
We have previously reported a strong association between HLA-DRB1*1301 and type 1 pediatric autoimmune hepatitis (PAH) and between HLA-DR*0405 and adult autoimmune hepatitis (AAH). Because human killer cell immunoglobulin-like ...
Treatment of Fabry's Disease with the Pharmacologic Chaperone Migalastat.
(Massachusetts Medical Society, 2016-08-11)
BACKGROUND:
Fabry's disease, an X-linked disorder of lysosomal α-galactosidase deficiency, leads to substrate accumulation in multiple organs. Migalastat, an oral pharmacologic chaperone, stabilizes specific mutant forms ...
Succinate-CoA ligase deficiency due to mutations in SUCLA2 and SUCLG1: phenotype and genotype correlations in 71 patients.
(John Wiley & Sons, Inc. All rights reserved, 2016-03-01)
BACKGROUND:
The encephalomyopathic mtDNA depletion syndrome with methylmalonic aciduria is associated with deficiency of succinate-CoA ligase, caused by mutations in SUCLA2 or SUCLG1. We report here 25 new patients with ...
Clinical epidemiology of acute hepatitis C in South America.
(Wiley, 2016-06)
There is scarce data pertaining to acute hepatitis C (aHC) infection in South America. We aimed to describe clinical characteristics and evolution of aHC in a South American cohort. A retrospective survey was conducted at ...
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
(Taylor & Francis Group's, 2016-01-21)
Many researchers, especially those new to the field, need to
determine which criteria are essential for demonstrating
autophagy, either for the purposes of their own research, or in
the capacity of a manuscript or grant ...
Hepatotoxicity Induced by Coxibs: How Concerned Should We Be?
(Taylor & Francis, 2016-08-26)
Introduction: The selective inhibitors of COX-2, coxibs, are nonsteroidal anti-inflammatory drugs (NSAIDs) that have much better gastrointestinal safety profile as compared with non-selective NSAIDs. In this review, we ...
Liver transplantation for hepatocellular carcinoma: evaluation of the alpha-fetoprotein model in a multicenter cohort from Latin America.
(Wiley, 2016-11-01)
BACKGROUND & AIMS:
The French alpha-fetoprotein (AFP) model has recently shown superior results compared to Milan criteria (MC) for prediction of hepatocellular carcinoma (HCC) recurrence after liver transplantation (LT) ...
Identifying patients at higher risk of hepatocellular carcinoma recurrence after liver transplantation in a multicenter cohort study from Argentina.
(Wolters Kluwer Health, Inc., 2016-04-28)
BACKGROUND AND AIM:
The Up-to-7 criteria on the basis of the explanted liver features categorize patients at higher risk of hepatocellular carcinoma (HCC) recurrence after liver transplantation (LT). The aim of this study ...
Association Between Cigarette Smoking Prevalence and Income Level: A Systematic Review and Meta-Analysis
(Oxford University Press, 2016-10-26)
Introduction
Previous evidence linked low socioeconomic status with higher smoking prevalence. Our objective was to assess the strength of this association in the world population, updating a previous work.
Methods
Systematic ...
Impacto de una intervención educativa para mejorar la adherencia a las recomendaciones sobre sueño seguro del lactante.
(Sociedad Argentina de Pediatria, 2016-04-25)
Introducción. Las campañas públicas en países
desarrollados con recomendaciones para el
sueño seguro del lactante lograron aumentar la
adherencia a la posición supina para dormir a
más del 70% y generaron, simultáneamente, ...