Browsing Centro Académico de Salud (CAS) by Subject "Hepatotoxicity"

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Hepatotoxicity Induced by Coxibs: How Concerned Should We Be?

Bessone, Fernando.; Hernandez, Nelia.; Roma, Marcelo.; Ridruejo, Ezequiel.; Mendizabal, Manuel.; et al. (Taylor & Francis, 2016-08-26)

Introduction: The selective inhibitors of COX-2, coxibs, are nonsteroidal anti-inflammatory drugs (NSAIDs) that have much better gastrointestinal safety profile as compared with non-selective NSAIDs. In this review, we ...
The Latin American DILI Registry Experience: A Successful Ongoing Collaborative Strategic Initiative.

Bessone, Fernando.; Hernandez, Nelia.; Lucena, Isabel.; Andrade, Raul.; Piñero, Federico.; Mendizabal, Manuel. (MDPI, 2016-02-25)

Drug induced liver injury (DILI) is a rare but well recognized serious adverse reaction. Pre-marketing studies may not detect liver injury, and DILI becomes very often apparent after the drug is launched to the market. ...