Browsing Centro Académico de Salud (CAS) by Author "Tate, Pablo."
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Glucocorticoid and progesterone mechanisms in photoreceptor survival
Marquioni-Ramella, Melisa.; Cubilla, Marisa.; Bermúdez, Vicente.; Tate, Pablo.; Marazita, Mariela.; Suburo, Angela. (Elsevier B.V. ScienceDirect, 2020-01-01)Abstract Death of retinal photoreceptors is the basis of prevalent blinding diseases. Since steroids might have a therapeutic role in retinal degenerations, we compared the protective effects of dexamethasone and progesterone ... -
Ilex paraguariensis extracts and its polyphenols prevent oxidative damage and senescence of human retinal pigment epithelium cells
Tate, Pablo.; Marazita, Mariela.; Marquioni, Melisa.; Suburo, Angela. (Elsevier Ltd. All rights reserved, 2020-04-01)Abstract Aged-related macular degeneration (AMD), a prevalent chronic disease leading to blindness, is associated with oxidative damage of the retinal pigment epithelium (RPE). Ilex paraguariensis (yerba mate, YM), widely ... -
IMT504 Provides Analgesia by Modulating Cell Infiltrate and Inflammatory Milieu in a Chronic Pain Model
Brumovsky, Pablo.; Villar, Marcelo.; Tate, Pablo.; Et al. (Springer [Commercial Publisher], 2021-09)Abstract IMT504 is a non-CPG, non-coding synthetic oligodeoxinucleotide (ODN) with immunomodulatory properties and a novel inhibitory role in pain transmission, exerting long-lasting analgesic effects upon multiple systemic ... -
New insights into oxidative stress and immune mechanisms involved in age-related macular degeneration tackled by novel therapies
Potilinski, María.; Tate, Pablo.; Lorenc, Valeria.; Et al. (Elsevier, 2021-05)Abstract The prevalence of age-related macular degeneration (AMD) has increased in the last years. Although anti-VEGF agents have improved the prognosis of exudative AMD, dry AMD has still devastating effects on elderly ...