Browsing by Subject "Rac1 inhibitors."

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Development of an Improved Guanidine-Based Rac1 Inhibitor with in vivo Activity against Non-Small Cell Lung Cancer

Bayo, Juan.; Fiore, Esteban.; Mazzolini, Guillermo.; Et al. (Wiley, 2021-03)

Abstract The Rho GTPase Rac1 is involved in the control of cytoskeleton reorganization and other fundamental cellular functions. Aberrant activity of Rac1 and its regulators is common in human cancer. In particular, ...