Browsing by Subject "Chronic pain"
Now showing items 1-3 of 3
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IMT504 blocks allodynia in rats with spared nerve injury by promoting the migration of mesenchymal stem cells and by favoring an anti-inflammatory milieu at the injure nerve
(International Association for the Study of Pain, 2021-09)IMT504, a noncoding, non-CpG oligodeoxynucleotide, modulates pain-like behavior in rats undergoing peripheral nerve injury, through mechanisms that remain poorly characterized. Here, we chose the spared nerve injury model ... -
Neuroactive steroids, nociception and neuropathic pain: A flashback to go forward.
(Elsevier Inc. All rights reserved., 2016-04-11)The present review discusses the potential role of neurosteroids / neuroactive steroids in the regulation of nociceptive and neuropathic pain, and recapitulates the current knowledge on the main mechanisms involved in ... -
Spinal neuropeptide expression and neuropathic behavior in the acute and chronic phases after spinal cord injury: Effects of progesterone administration.
(Elsevier Inc. All rights reserved., 2017-02)Patients with spinal cord injury (SCI) develop chronic pain that severely compromises their quality of life. We have previously reported that progesterone (PG), a neuroprotective steroid, could offer a promising therapeutic ...