Browsing by Author "Mendizabal, Manuel."
Now showing items 1-20 of 27
-
A Latin American survey on demographic aspects of hospitalized, decompensated cirrhotic patients and the resources for their management
Mendizabal, Manuel.; Vorobioff, Julio.; Contreras, Fernando.; Et al. (Elsevier, 2020-07)Abstract Introduction & objectives: Liver cirrhosis is a major cause of mortality worldwide. Adequate diagnosis and treatment of decompensating events requires of both medical skills and updated technical resources. The ... -
Chronic hepatitis C and chronic kidney disease: Advances, limitations and unchartered territories
Mendizabal, Manuel.; Reddy, K.R. (Wiley, 2017-01-20)Over the past few years, treatment options for chronic hepatitis C virus (HCV) infection have evolved dramatically. The current approved interferon-free direct-acting antiviral (DAA) regimens have been shown to be safe and ... -
Comparison of different prognostic scores for patients with cirrhosis hospitalized with SARS-CoV-2 infection
Mendizabal, Manuel.; Piñero, Federico.; Ridruejo, Ezequiel. (Springer, 2021-11)Abstract Introduction and objectives: Viral infections have been described to increase the risk of decompensation in patients with cirrhosis. We aimed to determine the effect of SARS-CoV-2 infection on outcome of hospitalized ... -
Developing multicenter consortia in liver disease in Latin America: Challenges and opportunities.
Mendizabal, Manuel.; Silva, Marcelo. (Wiley, 2017-06-07)The development of consortia has been useful for exploring challenging scenarios and uncharted territories in liver disease treatments. Several consortia already developed in the United States and Europe have become key ... -
A different gut microbiome linked to inflammation found in cirrhotic patients with and without hepatocellular carcinoma
Piñero, Federico.; Vazquez, Martín.; Baré, Patricia.; Rohr, Cristian.; Mendizabal, Manuel.; Sciara, Mariela.; Alonsoa, Cristina. (Elsevier, 2019-04-15)Abstract Introduction and aim: A pro-oncogenic intestinal microbiome was observed in murine models; however, no specific microbiome in patients with hepatocellular carcinoma (HCC) has been reported. We aimed to compare ... -
A different gut microbiome linked to inflammation found in cirrhotic patients with and without hepatocellular carcinoma.
Piñero, Federico.; Vazquez, Martín.; Baré, Patricia.; Rohr, Cristian.; Mendizabal, Manuel.; Sciarac, Mariela.; Alonsoa, Cristina.; et al. (Elsevier B.V. ScienceDirect, 2019-04-15)Abstract Introduction and aim: A pro-oncogenic intestinal microbiome was observed in murine models; however, no specific microbiome in patients with hepatocellular carcinoma (HCC) has been reported. We aimed to compare ... -
Direct-acting antiviral treatment failure in genotype 2 hepatitis C chronic infection
Piñero, Federico.; Mendizabal, Manuel.; Silva, Marcelo.; Et al. (Wiley, 2021-02)Comment J Viral Hepat . 2021 Feb;28(2):446-447. doi: 10.1111/jvh.13433. Epub 2020 Nov 18. Direct-acting antiviral treatment failure in genotype 2 hepatitis C chronic infection Ezequiel Ridruejo 1 2 3, Federico Piñero 2 ... -
Disease Progression in Patients With Hepatitis C Virus Infection Treated With Direct-Acting Antiviral Agents.
Mendizabal, Manuel.; Piñero, Federico.; Ridruejo, Ezequiel.; Et al. (Elsevier, 2020-10)Abstract Background & aims: Little is known about how a sustained virologic response (SVR) to treatment of hepatitis C virus infection with direct-acting antivirals (DAAs) affects patient mortality and development of new ... -
Drug-induced liver injury: A management position paper from the Latin American Association for Study of the liver
Mendizabal, Manuel.; Silva, Marcelo.; Bessone, Fernando.; Et al. (Elsevier, 2021-09)Abstract Idiosyncratic drug-induced liver injury (DILI) caused by xenobiotics (drugs, herbals and dietary supplements) is an uncommon cause of liver disease presenting with a wide range of phenotypes and disease severity, ... -
Hepatitis C Virus Infection: What Are We Currently Doing in Latin America About WHO's Proposals for 2030?
Mendizabal, Manuel.; Roblero, Juan P.; Arab, Juan.; Et al. (American Association for the Study of Liver Diseases, 2021-09)Hepatitis C virus (HCV) infection is a serious health problem worldwide. It has been estimated that it affects 1% of the global population, and most of these indi-viduals are unaware until the development ... -
Hepatotoxicity Induced by Coxibs: How Concerned Should We Be?
Bessone, Fernando.; Hernandez, Nelia.; Roma, Marcelo.; Ridruejo, Ezequiel.; Mendizabal, Manuel.; et al. (Taylor & Francis, 2016-08-26)Introduction: The selective inhibitors of COX-2, coxibs, are nonsteroidal anti-inflammatory drugs (NSAIDs) that have much better gastrointestinal safety profile as compared with non-selective NSAIDs. In this review, we ... -
Identification of optimal therapeutic window for steroid use in severe alcohol-associated hepatitis: A worldwide study
Mendizabal, Manuel.; Arab, Juan.; Díaz, Luis.; Et al. (Elsevier, 2021-11)Abstract Background & aims: Corticosteroids are the only effective therapy for severe alcohol-associated hepatitis (AH), defined by a model for end-stage liver disease (MELD) score >20. However, there are patients who may ... -
Impact of Public Health Policies on Alcohol-Associated Liver Disease in Latin America: An Ecological Multinational Study
Mendizabal, Manuel.; Díaz, Luis.; Idalsoaga, Francisco.; Et al. (Lippincott, Williams & Wilkins [Commercial Publisher], 2021-11)Abstract Background and aims: Alcohol-associated liver disease (ALD) is the leading cause of liver-related mortality in Latin America, yet the impact of public health policies (PHP) on liver disease is unknown. We aimed ... -
Incidence, risk factors, and outcomes related with neurological events after liver transplantation in adult and pediatric recipients.
Piñero, Federico.; Cheang, Yu.; Mendizabal, Manuel.; Cagliani, Joaquin.; Gonzalez, Ariel.; Pages, Josefina.; Colaci, Carla.; et al. (Wiley, 2018-02-07)Controversy exists whether NE after LT are more frequently observed in children or adults. We aimed to compare the incidence and outcomes for NE after LT in pediatric and adult recipients. A single-center cohort study, ... -
Incidence, risk factors, and outcomes related with neurological events after liver transplantation in adult and pediatric recipients.
Piñero, Federico.; Cheang, Yu.; Mendizabal, Manuel.; Cagliani, Joaquín.; Gonzalez, Ariel.; Pages, Josefina.; Colaci, Carla.; et al. (John Wiley & Sons A/S. Published by John Wiley & Sons Ltd, 2018-02-07)Abstract Controversy exists whether NE after LT are more frequently observed in children or adults. We aimed to compare the incidence and outcomes for NE after LT in pediatric and adult recipients. A single-center cohort ... -
Isolated Intrapulmonary Vascular Dilatations and the Risk of Developing Hepatopulmonary Syndrome in Liver Transplant Candidates.
Mendizabal, Manuel.; Goldberg, DS.; Piñero, Federico.; Arufe, Diego.; De la Fuente, María J.; Testa, Pablo.; Coronel, Matias.; et al. (Elsevier, 2017-08-01)BACKGROUND: The natural history of intrapulmonary vascular dilations (IPVD) and their impact on patient outcomes in the setting of portal hypertension has only been described in small series. AIMS: To assess the ... -
The Latin American DILI Registry Experience: A Successful Ongoing Collaborative Strategic Initiative.
Bessone, Fernando.; Hernandez, Nelia.; Lucena, Isabel.; Andrade, Raul.; Piñero, Federico.; Mendizabal, Manuel. (MDPI, 2016-02-25)Drug induced liver injury (DILI) is a rare but well recognized serious adverse reaction. Pre-marketing studies may not detect liver injury, and DILI becomes very often apparent after the drug is launched to the market. ... -
Ombitasvir / paritaprevir / ritonavir / dasabuvir ± ribavirina es segura y efectiva en el HCV - infectados pacientes en una vida real cohorte de América Latina .
Mendizabal, Manuel.; Haddad, Leila.; Gallardo, Patricia.; Ferrada, Alejandro.; Soza, Alejandro.; Adrover, Raul.; Aravena, Edmundo. (Wiley, 2017-03-29)Information about the use of ombitasvir/paritaprevir/ritonavir/dasabuvir ± ribavirin (OBV/PTV/r/DSV ± RBV) in real-clinical practice in Latin America is scarce. We aimed to confirm safety and effectiveness of OBV/PTV/r/DSV ± RBV ... -
Ombitasvir/paritaprevir/ritonavir/dasabuvir ± ribavirin is safe and effective in HCV-infected patients in a real-life cohort from Latin America.
Mendizabal, Manuel.; Haddad, Leila.; Gallardo, Patricia.; Ferrada, Alejandro.; Soza, Alejandro.; Adrover, Raul.; Aravena, Edmundo.; et al. (Wiley, 2017-09-01)Information about the use of ombitasvir/paritaprevir/ritonavir/dasabuvir ± ribavirin (OBV/PTV/r/DSV ± RBV) in real-clinical practice in Latin America is scarce. We aimed to confirm safety and effectiveness of OBV/PTV/r/DSV ± RBV ... -
Outbreak of hepatitis A in a post-vaccination era: High rate of co-infection with sexually transmitted diseases
Mendizabal, Manuel.; Marciano, Sebastian.; Arufe, Diego.; Et al. (Elsevier, 2020-11)Abstract Introduction and objectives: After hepatitis A (HAV) mandatory immunization in 2005 in Argentina, the incidence of HAV declined drastically. However, several new autochthonous cases of HAV have been reported since ...